SCHEMBL7133642

SCHEMBL7133642

CCCCCCCCCCCCN1c2ccccc2C(C)=CC1(C)C

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.46
ALDH1A1 P00352 5/20 0.45
CDC25A P30304 10/20 0.44
CES1 P23141 2/20 0.44
NPSR1 Q6W5P4 3/20 0.43
TSHR P16473 2/20 0.43
USP2 O75604 1/20 0.43
MAPK1 P28482 1/20 0.43
ALDH2 P05091 1/20 0.42
ALDH3A1 P30838 1/20 0.42
MCOLN3 Q8TDD5 1/20 0.41
KDM4E B2RXH2 1/20 0.40
MAPT P10636 1/20 0.40
KMT2A Q03164 1/20 0.40
GAA P10253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9074053 0.94 LMNA (0.48) LMNAALDH1A1CDC25ACES1NPSR1
SCHEMBL7879104 0.86 LMNA (0.54) LMNAALDH1A1NPSR1TSHRUSP2
SCHEMBL9166728 0.81 LMNA (0.53) LMNAALDH1A1NPSR1TSHRUSP2
SCHEMBL21160461 0.80 LMNA (0.53) LMNAALDH1A1NPSR1TSHRUSP2
SCHEMBL502503 0.78 ALDH1A1 (0.53) LMNAALDH1A1TSHRMAPK1KDM4E
SCHEMBL9073589 0.78 NPSR1 (0.47) LMNAALDH1A1NPSR1TSHRUSP2
SCHEMBL11667413 0.77 LMNA (0.43) LMNAALDH1A1CDC25ACES1NPSR1
SCHEMBL10092666 0.77 ALDH1A1 (0.45) LMNAALDH1A1TSHRMAPK1KDM4E
SCHEMBL2393621 0.76 LMNA (0.57) LMNAALDH1A1NPSR1TSHRUSP2
Iodide SCHEMBL27879085 0.75 CDC25A (0.43) LMNAALDH1A1CDC25ACES1ALDH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1325069-A1 THERMOPLASTIC RESINS STABILIZED BY BLENDS OF STERICALLY HINDERED PHENOLS,SECONDARY AMINES, AND LACTONES Uniroyal Chemical Company, Inc. (US) 2003-07-09 EP claimed
WO-2002031038-A1 THERMOPLASTIC RESINS STABILIZED BY BLENDS OF STERICALLY HINDERED PHENOLS, SECONDARY AMINES, AND LACTONES UNIROYAL CHEMICAL COMPANY, INC. (US) 2002-04-18 WO claimed
EP-1129133-A1 THERMOPLASTIC RESINS STABILIZED BY BLENDS OF STERICALLY HINDERED PHENOLS, SECONDARY AMINES, AND THIOETHERS UNIROYAL CHEMICAL COMPANY, Inc. (US) 2001-09-05 EP claimed
WO-2000027913-A1 THERMOPLASTIC RESINS STABILIZED BY BLENDS OF STERICALLY HINDERED PHENOLS, SECONDARY AMINES, AND THIOETHERS UNIROYAL CHEMICAL COMPANY, INC. (US) 2000-05-18 WO claimed