Fraxinol

Fraxinol

SCHEMBL7133703

COc1cc2oc(=O)ccc2c(OC)c1O

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4D Q08499 2/20 0.61
KDM4E B2RXH2 9/20 0.57
ALDH1A1 P00352 6/20 0.57
HSD17B10 Q99714 5/20 0.57
CYP3A4 P08684 3/20 0.57
CYP1A2 P05177 2/20 0.57
CYP2A6 P11509 2/20 0.57
CYP2C9 P11712 2/20 0.57
CYP2C19 P33261 2/20 0.57
CYP1A1 P04798 1/20 0.57
PGR P06401 1/20 0.57
ADORA3 P0DMS8 1/20 0.57
CYP2D6 P10635 1/20 0.57
KCNA2 P16389 1/20 0.57
TSHR P16473 1/20 0.57
MAOA P21397 1/20 0.57
CYP1B1 Q16678 1/20 0.57
CA9 Q16790 8/20 0.56
CA12 O43570 7/20 0.56
CA1 P00915 7/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30303166 0.88 CA9 (0.60) PDE4DKDM4EALDH1A1HSD17B10CYP3A4
5,6,7-Trimethoxycoumarin SCHEMBL4743900 0.85 ALDH1A1 (0.62) PDE4DKDM4EALDH1A1HSD17B10CYP3A4
SCHEMBL21623725 0.81 KDM4E (0.60) PDE4DKDM4EALDH1A1HSD17B10CYP3A4
SCHEMBL29779951 0.81 KDM4E (0.60) PDE4DKDM4EALDH1A1HSD17B10CYP3A4
SCHEMBL30498930 0.79 ALDH1A1 (0.55) PDE4DKDM4EALDH1A1HSD17B10CYP3A4
SCHEMBL7837457 0.78 KDM4E (0.69) PDE4DKDM4EALDH1A1HSD17B10CYP3A4
SCHEMBL31019383 0.77 CYP2A6 (0.62) PDE4DKDM4EALDH1A1HSD17B10CYP3A4
SCHEMBL15941538 0.76 PDE4D (1.00) PDE4DKDM4EALDH1A1HSD17B10CYP3A4
SCHEMBL3924718 0.75 CA9 (0.78) PDE4DKDM4EALDH1A1HSD17B10CYP3A4
SCHEMBL30098746 0.75 CA9 (0.78) PDE4DKDM4EALDH1A1HSD17B10CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117860636-A Composition containing lemon extract and application of composition in preparation of product with acne removing effect 广州明辉化妆品有限公司 2024-04-12 CN claimed
CN-116617211-B Application of composition in preparing medicine for treating surgical wound 山东第一医科大学附属省立医院(山东省立医院) 2023-11-28 CN claimed
CN-116617211-A Application of composition in preparing medicine for treating surgical wound 山东第一医科大学附属省立医院(山东省立医院) 2023-08-22 CN claimed
CN-116268070-A Polyphenol additive capable of improving frozen storage quality of non-rinsed minced fillet and application thereof 中南林业科技大学 2023-06-23 CN claimed
CN-111057033-B Preparation method of monomer compound in Chinese actinidia root and application of monomer compound in preparation of antitumor drugs 复旦大学 2022-11-08 CN claimed
CN-112107497-A High-stability sun-blocking cream and preparation method thereof 青岛姿之妍化妆品科技有限责任公司 2020-12-22 CN claimed
CN-112042490-A Lodging-resistant yield-increasing cultivation method for corn and lodging-resistant corn 中国农业大学 2020-12-08 CN claimed
CN-111991260-A Sunscreen cream based on modified fraxinus chinensis glycoside and preparation method thereof 青岛姿之妍化妆品科技有限责任公司 2020-11-27 CN claimed
CN-108948110-A A kind of Manchurian Ash Seed extract, extraction separation method and its application 西北大学 2018-12-07 CN claimed
CN-104447916-A Method for synthesizing fraxinol glycosides UNIV CHANGCHUN SCIENCE & TECH 2015-03-25 CN claimed
CN-104367486-A Application of fraxinol glucosides in uvioresistant cosmetics UNIV CHANGCHUN SCIENCE & TECH 2015-02-25 CN claimed
CN-103478430-A Preparation method of Nutritional nutritional synergist of livestock and poultry feed processing method YIYANG DOUBLE SHEEP TECHNOLOGY FEEDS CO LTD 2014-01-01 CN claimed
CN-103110700-A Fraxinus mandshurica extract for treating rheumatoid arthritis UNIV CHANGCHUN SCIENCE & TECH 2013-05-22 CN claimed
EP-1336602-A1 Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases Scaramuzzino, Giovanni (IT) 2003-08-20 EP claimed
CN-122036666-A Method for extracting aesculetin and application of aesculetin in plant disease control 西南大学 2026-05-15 CN disclosed
CN-122028804-A Flavanone compounds and their use as flavor modifiers 弗门尼舍有限公司 2026-05-12 CN disclosed
CN-120866083-B Endophytic fungus with functions of improving reversibility and promoting growth of water yeast Liu Kang and application thereof 东北林业大学 2026-05-12 CN disclosed
CN-101352202-B Method for formulating green feedstuff additive capable of substituting antibiotics in daily grain of chicken UNIV HUNAN AGRICULTURAL 2011-08-24 CN disclosed
CN-101352202-A Method for formulating green feedstuff additive capable of substituting antibiotics in daily grain of chicken UNIV HUNAN AGRICULTURAL (CN) 2009-01-28 CN disclosed
EP-1336602-A1 Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases Scaramuzzino, Giovanni (IT) 2003-08-20 EP disclosed