5,6,7-Trimethoxycoumarin

5,6,7-Trimethoxycoumarin

SCHEMBL4743900

COc1cc2oc(=O)ccc2c(OC)c1OC

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.62
KDM4E B2RXH2 8/20 0.62
HSD17B10 Q99714 5/20 0.62
CYP3A4 P08684 3/20 0.62
CYP2A6 P11509 2/20 0.62
CYP1A2 P05177 2/20 0.62
CYP1A1 P04798 1/20 0.62
PGR P06401 1/20 0.62
ADORA3 P0DMS8 1/20 0.62
CYP2D6 P10635 1/20 0.62
CYP2C9 P11712 1/20 0.62
KCNA2 P16389 1/20 0.62
TSHR P16473 1/20 0.62
MAOA P21397 1/20 0.62
CYP2C19 P33261 1/20 0.62
CYP1B1 Q16678 1/20 0.62
PDE4D Q08499 2/20 0.62
CA9 Q16790 7/20 0.61
CA12 O43570 6/20 0.61
CA1 P00915 6/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30303166 0.85 CA9 (0.60) ALDH1A1KDM4EHSD17B10CYP3A4CYP2A6
Fraxinol SCHEMBL7133703 0.85 PDE4D (0.61) ALDH1A1KDM4EHSD17B10CYP3A4CYP2A6
SCHEMBL29779951 0.81 KDM4E (0.60) ALDH1A1KDM4EHSD17B10CYP3A4CYP2A6
SCHEMBL21623725 0.81 KDM4E (0.60) ALDH1A1KDM4EHSD17B10CYP3A4CYP2A6
SCHEMBL31019383 0.81 CYP2A6 (0.62) ALDH1A1KDM4EHSD17B10CYP3A4CYP2A6
SCHEMBL15941538 0.77 PDE4D (1.00) ALDH1A1KDM4EHSD17B10CYP3A4CYP2A6
Bergapten SCHEMBL50066 0.77 ALDH1A1 (1.00) ALDH1A1KDM4EHSD17B10CYP3A4CYP2A6
Bergapten SCHEMBL29529284 0.77 ALDH1A1 (1.00) ALDH1A1KDM4EHSD17B10CYP3A4CYP2A6
Bergapten SCHEMBL4731782 0.77 ALDH1A1 (1.00) ALDH1A1KDM4EHSD17B10CYP3A4CYP2A6
Bergapten SCHEMBL15534211 0.76 ALDH1A1 (0.82) ALDH1A1KDM4EHSD17B10CYP3A4CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3749348-B1 COMPOSITION FOR THE PREVENTION AND TREATMENT OF DISEASES OF THE RESPIRATORY TRACT NEILOS S R L (IT) 2024-04-17 EP disclosed
EP-3687557-B1 COMPOSITION FOR THE PREVENTION AND/OR TREATMENT OF RESPIRATORY TRACT DISORDERS NEILOS S R L (IT) 2023-11-08 EP disclosed
EP-4153205-A1 COMPOSITION FOR THE PREVENTION AND THE TREATMENT OF DISEASES OF THE RESPIRATORY TRACT AND AS A STIMULANT OF THE IMMUNE SYSTEM Neilos S.r.l. (IT) 2023-03-29 EP disclosed
WO-2022168019-A1 COMPOSITION WITH IMMUNOSTIMULANT ACTION USEFUL FOR THE PREVENTION AND TREATMENT OF RESPIRATORY DISEASES Neilos S.r.l. (IT) 2022-08-11 WO disclosed
US-11351213-B2 Composition for the prevention and/or treatment of respiratory tract disorders Neilos S.r.l. (IT) 2022-06-07 US disclosed
WO-2021234660-A1 COMPOSITION FOR THE PREVENTION AND THE TREATMENT OF DISEASES OF THE RESPIRATORY TRACT AND AS A STIMULANT OF THE IMMUNE SYSTEM Neilos S.r.l. (IT) 2021-11-25 WO disclosed
US-20210046164-A1 COMPOSITION FOR THE PREVENTION AND TREATMENT OF DISEASES OF THE RESPIRATORY TRACT Neilos S.r.l. (IT) 2021-02-18 US disclosed
EP-3749348-A1 COMPOSITION FOR THE PREVENTION AND TREATMENT OF DISEASES OF THE RESPIRATORY TRACT Neilos S.r.l. (IT) 2020-12-16 EP disclosed
CN-112074291-A Composition for preventing and treating respiratory diseases 耐伊洛斯有限责任公司 2020-12-11 CN disclosed
US-20200254043-A1 COMPOSITION FOR THE PREVENTION AND/OR TREATMENT OF RESPIRATORY TRACT DISORDERS Neilos S.r.l. (IT) 2020-08-13 US disclosed
EP-3687557-A1 COMPOSITION FOR THE PREVENTION AND/OR TREATMENT OF RESPIRATORY TRACT DISORDERS Neilos S.r.l. (IT) 2020-08-05 EP disclosed
WO-2019154773-A1 COMPOSITION FOR THE PREVENTION AND TREATMENT OF DISEASES OF THE RESPIRATORY TRACT Neilos S.r.l. (IT) 2019-08-15 WO disclosed
WO-2019064255-A1 COMPOSITION FOR THE PREVENTION AND/OR TREATMENT OF RESPIRATORY TRACT DISORDERS Neilos S.r.l. (IT) 2019-04-04 WO disclosed
WO-2008100977-A2 CARBAMATES THERAPEUTIC RELEASE AGENTS AS AMIDASE INHIBITORS N.V. ORGANON (NL) 2008-08-21 WO disclosed