Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6134036 | 0.82 | USP2 (0.43) | USP2SMN1; SMN2GPR119CYP4F2CYP4A11 | |
| SCHEMBL4836593 | 0.81 | GPR4 (0.45) | USP2SMN1; SMN2GPR119CYP4F2CYP4A11 | |
| SCHEMBL18481419 | 0.80 | USP2 (0.43) | USP2SMN1; SMN2GPR119CYP4F2CYP4A11 | |
| SCHEMBL26044480 | 0.77 | CYP4F2 (0.42) | USP2SMN1; SMN2GPR119CYP4F2CYP4A11 | |
| SCHEMBL7682979 | 0.76 | USP2 (0.40) | USP2SMN1; SMN2GPR119CYP4F2CYP4A11 | |
| SCHEMBL597478 | 0.76 | GPR4 (0.46) | USP2SMN1; SMN2GPR119CYP4F2CYP4A11 | |
| SCHEMBL17861638 | 0.76 | USP2 (0.45) | USP2SMN1; SMN2GPR119CYP4F2CYP4A11 | |
| SCHEMBL17019234 | 0.75 | USP2 (0.37) | USP2SMN1; SMN2GPR119DDB1CRBN | |
| SCHEMBL21784672 | 0.75 | CYP4F2 (0.41) | USP2SMN1; SMN2CYP4F2CYP4A11CNR2 | |
| SCHEMBL7453562 | 0.74 | CYP4F2 (0.45) | USP2SMN1; SMN2GPR119CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1318978-A2 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | Abbott Laboratories (US) | 2003-06-18 | — | — | EP | disclosed |
| WO-2002024636-A2 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | ABBOTT LABORATORIES (US) | 2002-03-28 | — | — | WO | disclosed |