Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Valine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Valine SCHEMBL5667469 | 0.96 | SLC7A5 (0.36) | SLC7A5 | |
| Asparagine SCHEMBL5666134 | 0.94 | SLC7A5 (0.33) | SLC7A5 | |
| Valine SCHEMBL2189978 | 0.90 | SLC7A5 (0.41) | SLC7A5 | |
| Valine SCHEMBL3048383 | 0.90 | SLC7A5 (0.41) | SLC7A5 | |
| Valine SCHEMBL5801852 | 0.90 | SLC7A5 (0.41) | SLC7A5 | |
| Valine SCHEMBL4612496 | 0.90 | SLC7A5 (0.41) | SLC7A5 | |
| Asparagine SCHEMBL7139781 | 0.90 | PTGS1 (0.32) | SLC7A5 | |
| Valine SCHEMBL7135753 | 0.89 | ALOX15 (0.34) | SLC7A5 | |
| Valine SCHEMBL3496376 | 0.87 | SLC7A5 (0.43) | SLC7A5 | |
| Valine SCHEMBL3100209 | 0.87 | SLC7A5 (0.43) | SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6506731-B1 | Peptide or peptide-like compound(s) of the present invention appear to aid the elasticity and/or turgor of the skin | CONNECTIVE TISSUE IMAGINEERING LLC | 2003-01-14 | — | — | US | disclosed |