Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 9/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.47 |
| ▸ | CDC25A | P30304 | 1/20 | 0.46 |
| ▸ | ICMT | O60725 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4055511 | 0.96 | HRH2 (0.53) | HRH2HTR6CNR2CNR1HTR2A | |
| SCHEMBL8316249 | 0.85 | HTR6 (0.53) | HTR6HTR2C | |
| SCHEMBL4058347 | 0.82 | HRH2 (0.58) | HRH2HTR6HTR2AHTR2CHTR2B | |
| SCHEMBL4056205 | 0.82 | HTR6 (0.48) | HRH2HTR6CNR2CNR1HTR2A | |
| SCHEMBL27478068 | 0.80 | HRH2 (0.55) | HRH2CNR2CNR1CDC25AICMT | |
| SCHEMBL5749097 | 0.79 | CNR2 (0.41) | HRH2HTR6CNR2CNR1HTR2A | |
| SCHEMBL6781286 | 0.79 | HTR6 (0.52) | HRH2HTR6CNR2CNR1HTR2C | |
| SCHEMBL5937271 | 0.78 | HTR6 (0.57) | HTR6HTR2C | |
| SCHEMBL5342259 | 0.78 | CNR2 (0.53) | HTR6CNR2CNR1 | |
| SCHEMBL5339248 | 0.78 | HRH2 (0.56) | HRH2HTR6CNR2CNR1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0575430-B1 | PREPARATION OF A MEDICAMENT FOR THE TREATMENT OF ADDICTION TO DRUGS AND SUBSTANCES OF ABUSE | LUNDBECK & CO AS H (DK) | 1998-08-05 | — | — | EP | claimed |
| EP-0575429-B1 | TREATMENT OF COGNITIVE DISORDERS | LUNDBECK & CO AS H (DK) | 1995-12-06 | — | — | EP | claimed |
| US-5462948-A | Treatment of addiction to drugs and substances of abuse | H. LUNDBECK A/S (DK) | 1995-10-31 | — | — | US | claimed |
| US-5439922-A | Administering dopamine antagonists having reduced side effects | H. LUNDBECK A/S (DK) | 1995-08-08 | — | — | US | claimed |
| EP-0533824-B1 | PIPERIDYL-SUBSTITUTED INDOLES | LUNDBECK & CO AS H (DK) | 1994-11-09 | — | — | EP | claimed |
| EP-0575429-A1 | TREATMENT OF COGNITIVE DISORDERS. | LUNDBECK & CO AS H (DK) | 1993-12-29 | — | — | EP | claimed |
| EP-0575430-A1 | PREPARATION OF A MEDICAMENT FOR THE TREATMENT OF ADDICTION TO DRUGS AND SUBSTANCES OF ABUSE | H. LUNDBECK A/S (DK) | 1993-12-29 | — | — | EP | claimed |
| EP-0533824-A1 | PIPERIDYL-SUBSTITUTED INDOLES. | LUNDBECK & CO AS H (DK) | 1993-03-31 | — | — | EP | claimed |
| WO-1992015302-A1 | TREATMENT OF ADDICTION TO DRUGS AND SUBSTANCES OF ABUSE | H. LUNDBECK A/S (DK) | 1992-09-17 | — | — | WO | claimed |
| WO-1992015301-A1 | TREATMENT OF HYPERTENSION AND PERIPHERAL VASCULAR DISEASES | H. LUNDBECK A/S (DK) | 1992-09-17 | — | — | WO | claimed |
| WO-1992015303-A1 | TREATMENT OF COGNITIVE DISORDERS | H. LUNDBECK A/S (DK) | 1992-09-17 | — | — | WO | claimed |
| WO-1992000070-A1 | PIPERIDYL-SUBSTITUTED INDOLES | H. LUNDBECK A/S (DK) | 1992-01-09 | — | — | WO | claimed |
| EP-1068198-B1 | 5-HETEROARYL SUBSTITUTED INDOLES | LUNDBECK & CO AS H (DK) | 2003-05-28 | — | — | EP | disclosed |
| EP-0575430-B1 | PREPARATION OF A MEDICAMENT FOR THE TREATMENT OF ADDICTION TO DRUGS AND SUBSTANCES OF ABUSE | LUNDBECK & CO AS H (DK) | 1998-08-05 | — | — | EP | disclosed |
| EP-0575430-B1 | PREPARATION OF A MEDICAMENT FOR THE TREATMENT OF ADDICTION TO DRUGS AND SUBSTANCES OF ABUSE | LUNDBECK & CO AS H (DK) | 1998-08-05 | — | — | EP | disclosed |
| EP-0575429-B1 | TREATMENT OF COGNITIVE DISORDERS | LUNDBECK & CO AS H (DK) | 1995-12-06 | — | — | EP | disclosed |
| WO-1992015302-A1 | TREATMENT OF ADDICTION TO DRUGS AND SUBSTANCES OF ABUSE | H. LUNDBECK A/S (DK) | 1992-09-17 | — | — | WO | disclosed |
| WO-1992015302-A1 | TREATMENT OF ADDICTION TO DRUGS AND SUBSTANCES OF ABUSE | H. LUNDBECK A/S (DK) | 1992-09-17 | — | — | WO | disclosed |
| WO-1992000070-A1 | PIPERIDYL-SUBSTITUTED INDOLES | H. LUNDBECK A/S (DK) | 1992-01-09 | — | — | WO | disclosed |
| WO-1992000070-A1 | PIPERIDYL-SUBSTITUTED INDOLES | H. LUNDBECK A/S (DK) | 1992-01-09 | — | — | WO | disclosed |