Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | HTR1F | P30939 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | SCD | O00767 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7141281 | 0.81 | MAPK1 (0.44) | SMN1; SMN2MAPK1MEN1L3MBTL1KMT2A | |
| SCHEMBL7141826 | 0.76 | MAPK1 (0.46) | SMN1; SMN2MAPK1L3MBTL1 | |
| SCHEMBL8248389 | 0.76 | MAPK1 (0.40) | SMN1; SMN2MAPK1L3MBTL1 | |
| SCHEMBL9832235 | 0.75 | MAPK1 (0.53) | SMN1; SMN2MAPK1SRD5A1L3MBTL1KMT2A | |
| SCHEMBL10409949 | 0.69 | MAPK1 (0.79) | SMN1; SMN2MAPK1L3MBTL1KMT2AHTR1A | |
| SCHEMBL6198988 | 0.67 | MAPK1 (0.54) | SMN1; SMN2MAPK1L3MBTL1KMT2AHTR1A | |
| SCHEMBL14430433 | 0.66 | MAPK1 (0.40) | SMN1; SMN2MAPK1SRD5A1KMT2AHTR1F | |
| SCHEMBL11574443 | 0.65 | MAPK1 (0.46) | SMN1; SMN2MAPK1L3MBTL1KMT2AMAPT | |
| SCHEMBL6970399 | 0.65 | MAPK1 (0.59) | SMN1; SMN2MAPK1SRD5A1L3MBTL1HTR1A | |
| SCHEMBL11574947 | 0.65 | MAPK1 (0.54) | SMN1; SMN2MAPK1MEN1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675887-B1 | ANTIALLERGIC TRIAZOLOBENZAZEPINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2003-04-02 | — | — | EP | disclosed |