Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7141281 | 0.77 | MAPK1 (0.44) | MAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL7136245 | 0.76 | SMN1; SMN2 (0.43) | MAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL8248389 | 0.73 | MAPK1 (0.40) | MAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL8709456 | 0.64 | MAPK1 (0.72) | MAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL7142067 | 0.64 | MAPK1 (0.64) | MAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL7177984 | 0.64 | MAPK1 (0.64) | MAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL8207630 | 0.63 | L3MBTL1 (0.43) | MAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL9631976 | 0.63 | MAPK1 (0.73) | MAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL7140423 | 0.63 | SETD7 (0.43) | MAPK1 | |
| SCHEMBL7176890 | 0.62 | MAPK1 (0.61) | MAPK1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675887-B1 | ANTIALLERGIC TRIAZOLOBENZAZEPINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2003-04-02 | — | — | EP | disclosed |