Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 3/20 | 0.52 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.52 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL250581 | 0.85 | — | — | |
| SCHEMBL119275 | 0.85 | — | — | |
| SCHEMBL26111721 | 0.85 | LMNA (0.57) | GABRR1GABBR2GABBR1LMNAALDH1A1 | |
| SCHEMBL33836 | 0.85 | — | — | |
| SCHEMBL1193808 | 0.85 | LMNA (0.57) | GABRR1GABBR2GABBR1LMNAALDH1A1 | |
| SCHEMBL11348902 | 0.82 | — | — | |
| Fluoride SCHEMBL4617479 | 0.82 | — | — | |
| Water SCHEMBL9635107 | 0.82 | LMNA (0.53) | GABRR1GABBR2GABBR1LMNAALDH1A1 | |
| Glycerin SCHEMBL188342 | 0.82 | LMNA (0.64) | GABRR1GABBR2GABBR1LMNAALDH1A1 | |
| Water SCHEMBL2821624 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6503714-B1 | Contacting the sample with a probe under conditions in which said substance if present binds directly or indirectly to the probe, a plurality of nucleobases covalently attached to at least one strand of backbone comprising a plurality of atoms | ROCHE DIAGNOSTICS GMBH (DE) | 2003-01-07 | — | — | US | disclosed |
| US-6214549-B1 | CONTACTING SAMPLE WITH PROBE COMPRISING STEM AND BRANCH SUCH THAT SUBSTANCE IF PRESENT BINDS DIRECTLY OR INDIRECTLY TO PROBE; MIXING BINDING PRODUCT WITH CONJUGATE; REMOVING UNBOUND CONJUGATE FROM MIXTURE; DETERMINING PRESENCE OF CONJUGATE | ROCHE DIAGNOSTICS GMBH (DE) | 2001-04-10 | — | — | US | disclosed |