Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.68 |
| ▸ | MEN1 | O00255 | 5/20 | 0.68 |
| ▸ | HPGD | P15428 | 3/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5644218 | 0.84 | ALDH1A1 (0.73) | ALDH1A1LMNAKMT2AMEN1HPGD | |
| SCHEMBL7110795 | 0.83 | ALDH1A1 (0.70) | ALDH1A1LMNAKMT2AMEN1HPGD | |
| SCHEMBL3749553 | 0.81 | ALDH1A1 (1.00) | ALDH1A1LMNAKMT2AMEN1HPGD | |
| SCHEMBL5362218 | 0.81 | HPGD (1.00) | ALDH1A1LMNAKMT2AMEN1HPGD | |
| SCHEMBL4734710 | 0.81 | KMT2A (0.78) | ALDH1A1LMNAKMT2AMEN1HPGD | |
| SCHEMBL563504 | 0.81 | KMT2A (0.68) | ALDH1A1LMNAKMT2AMEN1HPGD | |
| SCHEMBL7132659 | 0.81 | ALDH1A1 (0.68) | ALDH1A1LMNAKMT2AMEN1HPGD | |
| SCHEMBL11299791 | 0.80 | HPGD (0.71) | ALDH1A1LMNAKMT2AMEN1HPGD | |
| SCHEMBL30489960 | 0.80 | ALDH1A1 (0.66) | ALDH1A1LMNAKMT2AMEN1HPGD | |
| SCHEMBL11012579 | 0.80 | HPGD (0.66) | ALDH1A1LMNAKMT2AMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030087306-A1 | Methods for identifying novel multimeric agents that modulate receptors | THERAVANCE BIOPHARMA R&D IP, LLC | 2003-05-08 | — | — | US | disclosed |