Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5885726 | 0.90 | RARB (0.45) | RARBKCNH2HRH3MAPK1TDP1 | |
| SCHEMBL27491939 | 0.87 | RARB (0.48) | RARBMAPK1L3MBTL1LMNAHSD17B10 | |
| SCHEMBL6857231 | 0.84 | FFAR1 (0.41) | RARBMAPK1TDP1LMNAHSD17B10 | |
| SCHEMBL2864794 | 0.84 | RARB (0.45) | RARBKCNH2HRH3MAPK1TDP1 | |
| SCHEMBL6858932 | 0.83 | GAA (0.42) | RARBMAPK1TDP1L3MBTL1LMNA | |
| SCHEMBL7139175 | 0.81 | PTPN11 (0.56) | RARBKCNH2HRH3TDP1L3MBTL1 | |
| SCHEMBL21157703 | 0.80 | RARB (0.64) | RARBKCNH2HRH3MAPK1TDP1 | |
| SCHEMBL5885728 | 0.78 | L3MBTL1 (0.46) | MAPK1TDP1L3MBTL1FDPSALOX5 | |
| SCHEMBL10739843 | 0.77 | RARB (0.57) | RARBNPC1RAB9ATP53TSHR | |
| SCHEMBL6858906 | 0.76 | NR1H4 (0.39) | RARBMAPK1LMNARAB9AFDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6509507-B2 | Reacting a 6-membered aromatic ring with 1,4- position ester or benzylic OH groups with a second aromatic in a palladium catalyzed cross-coupling; electroluminescence | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 2003-01-21 | — | — | US | disclosed |
| US-6458909-B1 | SOLID-STATE LIGHT SOURCES FOR A SERIES OF APPLICATIONS, PREDOMINANTLY IN THE FIELD OF DISPLAY ELEMENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 2002-10-01 | — | — | US | disclosed |
| US-20020087030-A1 | Polymerizable biaryls, process for their preparation and their use | MERCK PATENT GMBH (DE) | 2002-07-04 | — | — | US | disclosed |
| US-6323373-B1 | USED TO OBTAIN POLYMERS WHICH ARE USED AS ELECTROLUMINESCENCE MATERIALS | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 2001-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020087030-A1 | Polymerizable biaryls, process for their preparation and their use | PAH, TYR, PAICS | RARB 1893/4885KCNH2 1223/4885HRH3 145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.