SCHEMBL2864794

SCHEMBL2864794

CCOC(=O)c1ccc(C(=O)OCC)c2cc(-c3ccc(OCCC(C)CCCC(C)C)cc3)ccc12

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 2/20 0.45
TP53 P04637 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
FDPS P14324 1/20 0.41
NPC1 O15118 1/20 0.41
LMNA P02545 1/20 0.41
RAB9A P51151 1/20 0.41
HSD17B10 Q99714 1/20 0.41
ALOX5 P09917 1/20 0.41
ALOX15 P16050 3/20 0.40
RARA P10276 1/20 0.40
KCNH2 Q12809 1/20 0.39
HRH3 Q9Y5N1 1/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
MAPK1 P28482 1/20 0.38
EGFR P00533 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
GSTO1 P78417 1/20 0.38
ACACB O00763 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5885726 0.85 RARB (0.45) RARBTP53SMN1; SMN2FDPSNPC1
SCHEMBL7137206 0.84 RARB (0.48) RARBTP53SMN1; SMN2FDPSNPC1
SCHEMBL6857231 0.80 FFAR1 (0.41) RARBTP53SMN1; SMN2FDPSNPC1
SCHEMBL6858932 0.79 GAA (0.42) RARBTP53SMN1; SMN2FDPSNPC1
SCHEMBL5885728 0.76 L3MBTL1 (0.46) FDPSALOX5MAPK1EGFRTDP1
SCHEMBL2570786 0.76 RARB (0.44) RARBFDPSALOX5KMT2AMAPK1
SCHEMBL21157703 0.75 RARB (0.64) RARBKCNH2HRH3MEN1KMT2A
SCHEMBL2565984 0.73 RARB (0.41) RARBTP53FDPSALOX5KMT2A
SCHEMBL6860538 0.73 PTGS2 (0.42) FDPSALOX5MAPK1EGFRTDP1
SCHEMBL16340342 0.72 TDP1 (0.58) RARBTP53SMN1; SMN2FDPSLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7701129-B2 Polymeric fluorescent substance and polymer light-emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-04-20 US disclosed
US-20020122899-A1 Polymeric fluorescent substance and polymer light-emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED 2002-09-05 US disclosed