Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 3/20 | 0.77 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.65 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.36 |
| ▸ | CFD | P00746 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7079837 | 1.00 | OXTR (0.77) | OXTRAVPR1AADRB3ADRB1LMNA | |
| SCHEMBL7137761 | 1.00 | OXTR (0.77) | OXTRAVPR1AADRB3ADRB1LMNA | |
| SCHEMBL7089595 | 0.88 | OXTR (0.78) | OXTRAVPR1AADRB3ADRB1LMNA | |
| SCHEMBL4945256 | 0.87 | OXTR (1.00) | OXTRAVPR1AADRB3ADRB1LMNA | |
| SCHEMBL4936835 | 0.87 | OXTR (1.00) | OXTRAVPR1AADRB3ADRB1LMNA | |
| SCHEMBL4945247 | 0.87 | OXTR (1.00) | OXTRAVPR1AADRB3ADRB1LMNA | |
| SCHEMBL4936262 | 0.87 | OXTR (1.00) | OXTRAVPR1AADRB3ADRB1LMNA | |
| SCHEMBL4944776 | 0.87 | OXTR (1.00) | OXTRAVPR1AADRB3ADRB1LMNA | |
| SCHEMBL4944386 | 0.87 | OXTR (1.00) | OXTRAVPR1AADRB3ADRB1LMNA | |
| SCHEMBL4942988 | 0.83 | OXTR (0.71) | OXTRAVPR1AADRB3ADRB1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030212012-A1 | Pharmaceutically active pyrrolidine derivatives | MERCK SERONO SA (CH) | 2003-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030212012-A1 | Pharmaceutically active pyrrolidine derivatives | OXTR, CNR1, PRLHR | OXTR 1/4885AVPR1A 203/4885ADRB3 681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.