Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.50 |
| ▸ | ESR1 | P03372 | 4/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | PRKACA | P17612 | 1/20 | 0.49 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.49 |
| ▸ | GSR | P00390 | 1/20 | 0.45 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.43 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.43 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL714362 | 0.78 | ALDH1A1 (0.54) | MAPK1HTTRPS6KB1GSK3BTSHR | |
| SCHEMBL804992 | 0.76 | ESR2 (0.73) | MAPK1HTTESR2ESR1RECQL | |
| SCHEMBL541157 | 0.76 | ESR2 (0.78) | MAPK1HTTESR2ESR1RECQL | |
| SCHEMBL13085156 | 0.76 | RECQL (0.71) | MAPK1HTTESR2ESR1RECQL | |
| SCHEMBL16280947 | 0.76 | MAPK1 (0.65) | MAPK1HTTESR2ESR1RECQL | |
| SCHEMBL713812 | 0.76 | ESR2 (0.63) | MAPK1HTTESR2ESR1RECQL | |
| SCHEMBL21541088 | 0.76 | MAPK1 (0.55) | MAPK1HTTESR2ESR1RECQL | |
| SCHEMBL28338917 | 0.75 | ESR2 (0.76) | MAPK1HTTESR2ESR1RECQL | |
| SCHEMBL3257779 | 0.75 | ESR2 (0.66) | MAPK1HTTESR2ESR1RECQL | |
| SCHEMBL29351258 | 0.75 | ESR2 (0.66) | MAPK1HTTESR2ESR1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104194778-A | Phosphorus-oxygen group modified N-phenyl-benzimidazole electronic transmission material and synthesis method thereof and preparation method of electrophosphorescence device | UNIV HEILONGJIANG | 2014-12-10 | — | — | CN | disclosed |
| US-8771843-B2 | Fluorene derivative, organic compound, and light-emitting element, light-emitting device, and electronic device using the compound | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2014-07-08 | — | — | US | disclosed |
| CN-102952120-A | Compound for organic electroluminescent device and organic electroluminescent device using the same | E RAY OPTOELECTRONICS TECH CO | 2013-03-06 | — | — | CN | disclosed |
| US-20120049768-A1 | Fluorene Derivative, Organic Compound, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using the Compound | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120049768-A1 | Fluorene Derivative, Organic Compound, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using the Compound | AFF2, MAPRE2, AFF4 | MAPK1 2641/4885HTT 2214/4885ESR2 795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.