SCHEMBL7141082

SCHEMBL7141082

O=C(/C=C/c1ccco1)OC(=O)/C=C/c1ccco1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.67
POLB P06746 9/20 0.59
L3MBTL1 Q9Y468 5/20 0.59
ALDH1A1 P00352 3/20 0.59
KMT2A Q03164 4/20 0.57
MEN1 O00255 3/20 0.57
NPC1 O15118 1/20 0.57
BLM P54132 1/20 0.57
MCL1 Q07820 1/20 0.57
MASP2 O00187 1/20 0.56
F2 P00734 1/20 0.56
MAPT P10636 3/20 0.56
KDM4E B2RXH2 1/20 0.56
RAB9A P51151 1/20 0.56
TDP1 Q9NUW8 3/20 0.55
APEX1 P27695 2/20 0.55
CACNA1B Q00975 1/20 0.55
APBA1 Q02410 1/20 0.55
MAOA P21397 1/20 0.54
MAOB P27338 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7141083 1.00 HCAR2 (0.67) HCAR2POLBL3MBTL1ALDH1A1KMT2A
SCHEMBL7141086 0.92 HCAR2 (0.57) HCAR2POLBL3MBTL1ALDH1A1KMT2A
SCHEMBL1408805 0.87 HCAR2 (0.65) HCAR2POLBL3MBTL1ALDH1A1KMT2A
SCHEMBL6300803 0.85 HCAR2 (0.54) HCAR2POLBL3MBTL1ALDH1A1KMT2A
SCHEMBL1286940 0.85 POLB (0.67) HCAR2POLBL3MBTL1ALDH1A1KMT2A
SCHEMBL1286936 0.85 POLB (0.67) HCAR2POLBL3MBTL1ALDH1A1KMT2A
SCHEMBL11433827 0.85 POLB (0.56) HCAR2POLBL3MBTL1ALDH1A1KMT2A
SCHEMBL7142741 0.84 ALDH1A1 (0.67) HCAR2POLBL3MBTL1ALDH1A1KMT2A
SCHEMBL7142739 0.84 ALDH1A1 (0.67) HCAR2POLBL3MBTL1ALDH1A1KMT2A
SCHEMBL7141925 0.84 L3MBTL1 (0.67) HCAR2POLBL3MBTL1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6506863-B2 Used as crosslinking agents for olefin polymers BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2003-01-14 US claimed
US-20020137881-A1 Esters of 3-(2-furyl)-2propenoic acid with diols BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2002-09-26 US claimed
EP-1216999-A1 Esters of the 3-(2-furyl)-2-propenoic acid with diols Basell Poliolefine Italia S.p.A. (IT) 2002-06-26 EP claimed
US-11837711-B2 Silicon-based energy storage devices with anhydride containing electrolyte additives ENEVATE CORPORATION (US) 2023-12-05 US disclosed
US-11837711-B2 Silicon-based energy storage devices with anhydride containing electrolyte additives ENEVATE CORPORATION (US) 2023-12-05 US disclosed
US-20210167361-A1 SILICON-BASED ENERGY STORAGE DEVICES WITH ANHYDRIDE CONTAINING ELECTROLYTE ADDITIVES ENEVATE CORPORATION 2021-06-03 US disclosed
US-10957898-B2 Silicon-based energy storage devices with anhydride containing electrolyte additives ENEVATE CORPORATION (US) 2021-03-23 US disclosed
US-20200203711-A1 SILICON-BASED ENERGY STORAGE DEVICES WITH ANHYDRIDE CONTAINING ELECTROLYTE ADDITIVES ENEVATE CORPORATION 2020-06-25 US disclosed
US-6506863-B2 Used as crosslinking agents for olefin polymers BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2003-01-14 US disclosed
US-20020137881-A1 Esters of 3-(2-furyl)-2propenoic acid with diols BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2002-09-26 US disclosed
EP-1216999-A1 Esters of the 3-(2-furyl)-2-propenoic acid with diols Basell Poliolefine Italia S.p.A. (IT) 2002-06-26 EP disclosed