Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.61 |
| ▸ | CES2 | O00748 | 1/20 | 0.61 |
| ▸ | CES1 | P23141 | 1/20 | 0.61 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | ELANE | P08246 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetophenone SCHEMBL25304274 | 0.94 | CES2 (0.68) | SRD5A2CES2CES1NR4A1ALDH1A1 | |
| Acetone SCHEMBL29156010 | 0.92 | SRD5A2 (0.65) | SRD5A2CES2CES1NR4A1ALDH1A1 | |
| SCHEMBL31186097 | 0.92 | SRD5A2 (0.64) | SRD5A2CES2CES1NR4A1SMN1; SMN2 | |
| SCHEMBL2610307 | 0.89 | ALDH1A1 (0.70) | SRD5A2CES2CES1ALDH1A1SMN1; SMN2 | |
| SCHEMBL50462 | 0.89 | SRD5A2 (0.74) | SRD5A2CES2CES1NR4A1ALDH1A1 | |
| SCHEMBL9442387 | 0.89 | SRD5A2 (0.74) | SRD5A2CES2CES1NR4A1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4594202 | 0.87 | SRD5A2 (0.71) | SRD5A2CES2CES1NR4A1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4594201 | 0.87 | SRD5A2 (0.71) | SRD5A2CES2CES1NR4A1ALDH1A1 | |
| Bicarbonate SCHEMBL9817101 | 0.87 | SRD5A2 (0.71) | SRD5A2CES2CES1NR4A1ALDH1A1 | |
| Acetophenone SCHEMBL28412109 | 0.87 | MAPT (0.58) | CES2CES1ALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1714778-B1 | LAMINATE AND PROCESS FOR PRODUCING THE SAME | TOKUYAMA CORP (JP) | 2018-11-21 | — | — | EP | disclosed |
| CN-103426743-B | The cutting method of semiconductor wafer and the semiconductor machining cutting belt for this method | 古河电气工业株式会社 | 2017-12-08 | — | — | CN | disclosed |
| US-9588257-B2 | Photochromic curable composition | TOKUYAMA CORPORATION (JP) | 2017-03-07 | — | — | US | disclosed |
| EP-2554624-B1 | PHOTOCHROMIC CURABLE COMPOSITION | TOKUYAMA CORP (JP) | 2014-11-05 | — | — | EP | disclosed |
| US-20140146285-A1 | PHOTOCHROMIC CURABLE COMPOSITION | TOKUYAMA CORPORATION (JP) | 2014-05-29 | — | — | US | disclosed |
| EP-2733155-A1 | PHOTOCHROMIC CURABLE COMPOSITION | Tokuyama Corporation (JP) | 2014-05-21 | — | — | EP | disclosed |
| US-8663508-B2 | Photochromic curable composition | TOKUYAMA CORPORATION (JP) | 2014-03-04 | — | — | US | disclosed |
| US-8529789-B2 | Curable composition | TOKUYAMA CORPORATION (JP) | 2013-09-10 | — | — | US | disclosed |
| EP-2554624-A1 | PHOTOCHROMIC CURABLE COMPOSITION | Tokuyama Corporation (JP) | 2013-02-06 | — | — | EP | disclosed |
| US-20130015416-A1 | PHOTOCHROMIC CURABLE COMPOSITION | TOKUYAMA CORPORATION (JP) | 2013-01-17 | — | — | US | disclosed |
| EP-1445257-A1 | CHROMENE COMPOUND | Tokuyama Corporation (JP) | 2004-08-11 | — | — | EP | disclosed |
| US-6723859-B2 | BASE STRUCTURE IS A CHROMENE(3,2-A)FLUORENE RING CONTAINING SPIRO-FUSED RINGS; PHOTOCHROMIC LENSES; LARGE FADING RATE, LESS COLOR WHEN DETERIORATED, AND EXCELLENT LIGHT RESISTANCE IN THE PHOTOCHROMIC PROPERTIES | TOKUYAMA CORPORATION (JP) | 2004-04-20 | — | — | US | disclosed |
| US-6698883-B2 | COLOR DENSITY AND A LARGE FADING RATE, HARDNESS, HEAT RESISTANCE AND SHOCK RESISTANCE; AS OPTICAL MATERIAL SUCH AS A PHOTOCHROMIC LENS MATERIAL | TOKUYAMA CORPORATION (JP) | 2004-03-02 | — | — | US | disclosed |
| US-6646104-B1 | An optical material in a field where a high degree of refractive index is desired as represented by photochromic plastic lenses. | TOKUYAMA CORPORATION (JP) | 2003-11-11 | — | — | US | disclosed |
| US-20030096117-A1 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2003-05-22 | — | — | US | disclosed |
| EP-1291388-A1 | CURABLE COMPOSITION AND PHOTOCHROMIC CURED ARTICLE | TOKUYAMA CORPORATION (JP) | 2003-03-12 | — | — | EP | disclosed |
| US-20030008958-A1 | Curable composition and photochromic cured article | TOKUYAMA CORPORATION (JP) | 2003-01-09 | — | — | US | disclosed |
| EP-1184379-A1 | CHROMENE COMPOUND | TOKUYAMA CORPORATION (JP) | 2002-03-06 | — | — | EP | disclosed |
| EP-1149830-A1 | PROCESS FOR PRODUCTION OF SULFUR COMPOUNDS | TOKUYAMA CORPORATION (JP) | 2001-10-31 | — | — | EP | disclosed |
| EP-1130038-A1 | CURABLE COMPOSITION | TOKUYAMA CORPORATION (JP) | 2001-09-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030096117-A1 | Chromene compound | SMARCE1, SMARCD2, SMARCB1 | SRD5A2 2589/4885CES2 1746/4885CES1 3543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.