Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CCR6 | P51684 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7694380 | 0.82 | ALDH1A1 (0.62) | ALDH1A1MAPTHPGDSIGMAR1TDP1 | |
| Benzyl Dimethylcarbamate SCHEMBL5134244 | 0.82 | ALDH1A1 (0.62) | ALDH1A1MAPTHPGDSIGMAR1TDP1 | |
| Benzyl Dimethylcarbamate SCHEMBL14031385 | 0.82 | ALDH1A1 (0.62) | ALDH1A1MAPTHPGDSIGMAR1TDP1 | |
| Benzyl Dimethylcarbamate SCHEMBL20401678 | 0.82 | ALDH1A1 (0.62) | ALDH1A1MAPTHPGDSIGMAR1TDP1 | |
| SCHEMBL250619 | 0.80 | ALDH1A1 (0.60) | ALDH1A1MAPTHPGDSIGMAR1TDP1 | |
| SCHEMBL40190 | 0.80 | ALDH1A1 (0.51) | ALDH1A1MAPTHPGDSIGMAR1TDP1 | |
| SCHEMBL6050874 | 0.80 | ALDH1A1 (0.54) | ALDH1A1MAPTHPGDTDP1HCAR2 | |
| SCHEMBL25964356 | 0.80 | F13A1 (0.50) | ALDH1A1MAPTHPGDSIGMAR1TDP1 | |
| SCHEMBL1849023 | 0.80 | MAPT (0.42) | ALDH1A1MAPTSLC6A2SLC6A3KMT2A | |
| SCHEMBL26945299 | 0.79 | ALDH1A1 (0.50) | ALDH1A1MAPTHPGDSIGMAR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1321151-A1 | ANTIPARKINSONISM DRUGS | SHIONOGI & CO., LTD. (JP) | 2003-06-25 | — | — | EP | disclosed |