Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F13A1 | P00488 | 1/20 | 0.50 |
| ▸ | TGM2 | P21980 | 1/20 | 0.50 |
| ▸ | TGM1 | P22735 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CCR6 | P51684 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367495 | 0.89 | ALDH1A1 (0.58) | F13A1TGM2TGM1ALDH1A1CCR6 | |
| SCHEMBL25978639 | 0.84 | ALDH1A1 (0.53) | F13A1TGM2TGM1ALDH1A1CCR6 | |
| SCHEMBL31697957 | 0.84 | ALDH1A1 (0.53) | F13A1TGM2TGM1ALDH1A1CCR6 | |
| SCHEMBL5540531 | 0.84 | F13A1 (0.51) | F13A1TGM2TGM1ALDH1A1CCR6 | |
| SCHEMBL17304989 | 0.83 | TGM2 (0.44) | F13A1TGM2TGM1ALDH1A1CCR6 | |
| SCHEMBL17067258 | 0.83 | ALDH1A1 (0.56) | F13A1TGM2TGM1ALDH1A1CCR6 | |
| SCHEMBL25787612 | 0.82 | ALDH1A1 (0.50) | F13A1TGM2TGM1ALDH1A1CCR6 | |
| SCHEMBL2724661 | 0.81 | ALDH1A1 (0.53) | F13A1TGM2TGM1ALDH1A1CCR6 | |
| SCHEMBL553299 | 0.81 | ALDH1A1 (0.53) | F13A1TGM2TGM1ALDH1A1CCR6 | |
| SCHEMBL13181407 | 0.81 | LTB4R (0.56) | F13A1TGM2TGM1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4223318-A1 | ANTITUMOR COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Duality Biologics (Suzhou) Co., Ltd. (CN) | 2023-08-09 | — | — | EP | disclosed |