Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 12/20 | 0.44 |
| ▸ | THRA | P10827 | 4/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 7/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6455630 | 0.81 | MEN1 (0.45) | MEN1NR1I2KMT2ATHRBTHRA | |
| SCHEMBL5760588 | 0.79 | MEN1 (0.55) | MEN1NR1I2KMT2ATHRBTHRA | |
| SCHEMBL6343976 | 0.78 | MEN1 (0.50) | MEN1NR1I2KMT2ATHRBTHRA | |
| SCHEMBL5565457 | 0.78 | MEN1 (0.42) | MEN1NR1I2KMT2ATHRBTHRA | |
| SCHEMBL9166052 | 0.77 | MEN1 (0.54) | MEN1NR1I2KMT2ATHRBTHRA | |
| SCHEMBL10667190 | 0.76 | MEN1 (0.55) | MEN1NR1I2KMT2ATHRBTHRA | |
| SCHEMBL7890517 | 0.75 | THRB (0.41) | MEN1NR1I2KMT2ATHRBTHRA | |
| SCHEMBL6490769 | 0.74 | MEN1 (0.46) | MEN1NR1I2KMT2ATHRBTHRA | |
| SCHEMBL11460749 | 0.73 | MEN1 (0.51) | MEN1NR1I2KMT2ATHRBTHRA | |
| SCHEMBL7919792 | 0.73 | MEN1 (0.56) | MEN1NR1I2KMT2ATHRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1114046-B1 | INTERLEUKIN-5 INHIBITING 6-AZAURACIL DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2003-04-23 | — | — | EP | disclosed |