Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | FASN | P49327 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 2/20 | 0.36 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.33 |
| ▸ | ACP1 | P24666 | 2/20 | 0.33 |
| ▸ | CDC25B | P30305 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10073523 | 1.00 | CYP1A2 (0.39) | CYP1A2POLBFASNSTAT3DAGLA | |
| SCHEMBL13282110 | 0.94 | MEN1 (0.38) | CYP1A2POLBFASNSTAT3DAGLA | |
| SCHEMBL6864572 | 0.79 | CYP1A2 (0.43) | CYP1A2POLBFASNSTAT3DAGLA | |
| SCHEMBL712684 | 0.75 | POLB (0.41) | CYP1A2POLBFASNDAGLA | |
| SCHEMBL712649 | 0.70 | MMP2 (0.44) | MEN1HTTKMT2A | |
| SCHEMBL713868 | 0.69 | POLB (0.34) | CYP1A2POLBFASNSTAT3DAGLA | |
| SCHEMBL713616 | 0.69 | POLB (0.34) | CYP1A2POLBFASNSTAT3DAGLA | |
| SCHEMBL14715934 | 0.69 | CYP1A2 (0.49) | CYP1A2POLBFASNSTAT3DAGLA | |
| SCHEMBL9323706 | 0.68 | CYP1A2 (0.40) | CYP1A2POLBFASNSTAT3DAGLA | |
| SCHEMBL27584515 | 0.67 | CYP1A2 (0.46) | CYP1A2POLBFASNDAGLAPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124794-B2 | Method for the asymmetric synthesis of beta-lactone compounds | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2012-02-28 | — | — | US | claimed |
| US-20100173982-A1 | NOVEL METHOD FOR THE ASYMMETRIC SYNTHESIS OF BETA-LACTONE COMPOUNDS | THE BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2010-07-08 | — | — | US | claimed |
| US-20060258620-A1 | Novel method for the asymmetric synthesis of beta-lactone compounds | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2006-11-16 | — | — | US | claimed |
| US-8124794-B2 | Method for the asymmetric synthesis of beta-lactone compounds | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2012-02-28 | — | — | US | disclosed |
| US-20100173982-A1 | NOVEL METHOD FOR THE ASYMMETRIC SYNTHESIS OF BETA-LACTONE COMPOUNDS | THE BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2010-07-08 | — | — | US | disclosed |
| US-7728153-B2 | Method for the asymmetric synthesis of beta-lactone compounds | THE BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2010-06-01 | — | — | US | disclosed |
| US-20060258620-A1 | Novel method for the asymmetric synthesis of beta-lactone compounds | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2006-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100173982-A1 | NOVEL METHOD FOR THE ASYMMETRIC SYNTHESIS OF BETA-LACTONE COMPOUNDS | FASN, COASY, FADS1 | CYP1A2 768/4885POLB 1749/4885FASN 1/4885 |
| US-20060258620-A1 | Novel method for the asymmetric synthesis of beta-lactone compounds | FASN, COASY, FADS1 | CYP1A2 768/4885POLB 1749/4885FASN 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.