Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | PRCP | P42785 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7138988 | 1.00 | HTR1A (0.32) | HTR1ASLC6A2SLC6A4SLC6A3GID4 | |
| SCHEMBL7143994 | 0.84 | MAPK1 (0.37) | PRCP | |
| SCHEMBL7143061 | 0.81 | GID4 (0.48) | GID4 | |
| SCHEMBL4273307 | 0.81 | PRCP (0.45) | SLC6A2SLC6A4SLC6A3GID4PRCP | |
| SCHEMBL7138440 | 0.78 | PRCP (0.38) | GID4PRCP | |
| SCHEMBL7143984 | 0.77 | HDAC1 (0.33) | PRCP | |
| SCHEMBL7145701 | 0.76 | PRCP (0.44) | SLC6A2SLC6A4SLC6A3PRCP | |
| SCHEMBL7143821 | 0.76 | KDM1A (0.37) | PRCP | |
| SCHEMBL7142187 | 0.76 | PRCP (0.44) | PRCP | |
| SCHEMBL7143820 | 0.76 | KDM1A (0.37) | PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0966464-B1 | SUBSTITUTED 2,4-DIAMINOPYRIMIDINES | BASILEA PHARMACEUTICA AG (CH) | 2003-05-28 | — | — | EP | disclosed |
| US-6114330-A | BACTERICIDES | HOFFMANN-LA ROCHE INC. (US) | 2000-09-05 | — | — | US | disclosed |
| EP-0966464-A1 | SUBSTITUTED 2,4-DIAMINOPYRIMIDINES | F. HOFFMANN-LA ROCHE AG (CH) | 1999-12-29 | — | — | EP | disclosed |
| WO-1998039328-A1 | SUBSTITUTED 2,4-DIAMINOPYRIMIDINES | F.HOFFMANN-LA ROCHE AG (CH) | 1998-09-11 | — | — | WO | disclosed |