SCHEMBL7139031

SCHEMBL7139031

CC(C)(c1cc(Cl)c(OCC2CO2)c(Cl)c1)c1cc(Cl)c(OCC2CO2)c(Cl)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.55
TSHR P16473 4/20 0.55
TP53 P04637 3/20 0.55
MAPT P10636 2/20 0.55
HPGD P15428 2/20 0.55
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
HIF1A Q16665 2/20 0.55
CYP1A2 P05177 1/20 0.55
PPARG P37231 1/20 0.55
CYP3A4 P08684 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
GLA P06280 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
MAPK1 P28482 1/20 0.37
PKM P14618 2/20 0.34
LMNA P02545 1/20 0.34
GAA P10253 1/20 0.34
VDR P11473 1/20 0.33
PTPN1 P18031 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2830269 0.85 ALDH1A1 (0.60) ALDH1A1TSHRTP53MAPTHPGD
SCHEMBL12670352 0.84 MAPT (0.42) ALDH1A1TSHRTP53MAPTHPGD
SCHEMBL1104781 0.84 ALDH1A1 (0.55) ALDH1A1TSHRTP53MAPTHPGD
SCHEMBL1905766 0.83 MAPT (0.41) ALDH1A1TSHRTP53MAPTHPGD
SCHEMBL12670358 0.82 MAPT (0.40) ALDH1A1TSHRTP53MAPTHPGD
SCHEMBL12670357 0.82 ALDH1A1 (0.40) ALDH1A1TSHRTP53MAPTHPGD
SCHEMBL2230671 0.81 ALDH1A1 (0.47) ALDH1A1TSHRTP53MAPTHPGD
SCHEMBL12670364 0.81 ALDH1A1 (0.39) ALDH1A1TSHRTP53MAPTHPGD
SCHEMBL12670360 0.81 ALDH1A1 (0.39) ALDH1A1TSHRTP53MAPTHPGD
SCHEMBL13099338 0.81 ALDH1A1 (0.55) ALDH1A1TSHRTP53MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1466611-A low temperature adhesive composition 住友电木株式会社 2004-01-07 CN disclosed
US-6632523-B1 Polyimidesiloxane made from a dianhydride, an aromatic diamine and a siloxanediamine, an epoxy resin, and a cyanate; tape SUMITOMO BAKELITE COMPANY LIMITED (JP) 2003-10-14 US disclosed
WO-2002026888-A2 LOW TEMPERATURE BONDING ADHESIVE COMPOSITION SUMITOMO BAKELITE COMPANY LIMITED (JP) 2002-04-04 WO disclosed
EP-0199564-B1 POLYHYDROXY POLYETHER, PROCESS FOR ITS PRODUCTION AND ITS USE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-03-06 EP disclosed
US-4921890-A Process for improving polymer substrate properties, and flame retardancy modified polymers produced thereby INTERA COMPANY, LTD. (US) 1990-05-01 US disclosed
EP-0294531-A2 Treatment of polymer substrates Intera Company, Ltd (US) 1988-12-14 EP disclosed
EP-0268713-A1 Demulsifier composition and method of use thereof PETROLITE CORPORATION (US) 1988-06-01 EP disclosed
US-4675373-A GAS BARRIER MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1987-06-23 US disclosed
US-4626379-A REACTION PRODUCT OF BLEND OF POLYOXYALKYLENE OXIDE COPOLYMER AND VINYL MONOMER PETROLITE CORPORATION (US) 1986-12-02 US disclosed
EP-0199564-A2 Polyhydroxy polyether, process for its production and its use MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1986-10-29 EP disclosed
US-4502977-A REACTION PRODUCT OF BLEND OF OXYALKYLATED MATERIALS WITH VINYL MONOMER PETROLITE CORPORATION (US) 1985-03-05 US disclosed
US-4119640-A ACRYLIC OR METHACRYLIC ACID, DIEPOXIDES, INKS, HEAT OR RADIATION CURABLE COATINGS UNION CARBIDE CORPORATION (US) 1978-10-10 US disclosed