Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.40 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7742482 | 0.91 | MEN1 (0.52) | NPC1RAB9AHPGDMEN1KMT2A | |
| SCHEMBL6612323 | 0.82 | NAMPT (0.55) | NPC1RAB9AMEN1KMT2ACYP1A2 | |
| SCHEMBL6611989 | 0.82 | SLC6A9 (0.41) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL7736656 | 0.82 | POLB (0.43) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL4683414 | 0.80 | KCNJ11 (0.42) | NPC1RAB9AHPGDMEN1KMT2A | |
| SCHEMBL4683418 | 0.80 | KCNJ11 (0.42) | NPC1RAB9AHPGDMEN1KMT2A | |
| SCHEMBL6612989 | 0.80 | RXFP1 (0.52) | MEN1KMT2AALDH1A1KDM4ECYP3A4 | |
| SCHEMBL6614448 | 0.80 | CYP11B1 (0.54) | NPC1RAB9AMEN1KMT2ACYP1A2 | |
| SCHEMBL6612032 | 0.78 | KMT2A (0.49) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL6617069 | 0.78 | KCNJ11 (0.56) | RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003506355-A | — | — | 2003-02-18 | — | — | JP | claimed |
| EP-1198456-A2 | POTASSIUM CHANNEL OPENERS | Abbott Laboratories (US) | 2002-04-24 | — | — | EP | claimed |
| WO-2001009096-A2 | POTASSIUM CHANNEL OPENERS | ABBOTT LABORATORIES (US) | 2001-02-08 | — | — | WO | claimed |