Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 15/20 | 0.51 |
| ▸ | MMP1 | P03956 | 5/20 | 0.46 |
| ▸ | MMP13 | P45452 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7140732 | 0.77 | MMP1 (0.66) | MMP1MMP13 | |
| SCHEMBL7134718 | 0.73 | MMP1 (0.58) | ADAM17MMP1MMP13 | |
| SCHEMBL7133708 | 0.71 | MMP1 (0.57) | ADAM17MMP1MMP13 | |
| SCHEMBL7137896 | 0.69 | MMP1 (0.57) | ADAM17MMP1MMP13 | |
| SCHEMBL8474485 | 0.69 | MMP1 (0.70) | ADAM17MMP1MMP13 | |
| SCHEMBL7134745 | 0.69 | MMP1 (0.55) | ADAM17MMP1MMP13 | |
| SCHEMBL7356665 | 0.69 | ADAM17 (0.56) | ADAM17MMP1MMP13 | |
| SCHEMBL7139246 | 0.67 | MMP1 (0.56) | ADAM17MMP1MMP13 | |
| SCHEMBL7139183 | 0.67 | MMP1 (0.59) | ADAM17MMP1MMP13 | |
| SCHEMBL7354772 | 0.67 | ADAM17 (0.58) | ADAM17MMP1MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041072-B1 | Dioxocyclopentyl hydroxamic acids | PFIZER PROD INC (US) | 2003-07-16 | — | — | EP | disclosed |
| US-6214870-B1 | ANTIARTHRITIC AGENTS; ANTICANCER AGENTS | PFIZER INC | 2001-04-10 | — | — | US | disclosed |
| EP-1041072-A1 | Dioxocyclopentyl hydroxamic acids | Pfizer Products Inc. (US) | 2000-10-04 | — | — | EP | disclosed |