Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3827605 | 0.79 | APP (0.33) | APP | |
| SCHEMBL13803857 | 0.76 | APP (0.33) | CA2APP | |
| SCHEMBL6276420 | 0.76 | APP (0.33) | CA2APP | |
| SCHEMBL12744068 | 0.74 | APP (0.33) | APP | |
| SCHEMBL8833046 | 0.74 | APP (0.33) | APP | |
| SCHEMBL23671782 | 0.74 | APP (0.33) | APP | |
| SCHEMBL3792829 | 0.74 | CA2 (0.33) | CA2APP | |
| SCHEMBL19011946 | 0.74 | APP (0.33) | APP | |
| SCHEMBL75036 | 0.74 | APLNR (0.35) | APP | |
| SCHEMBL13130047 | 0.74 | APP (0.33) | APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2801574-B1 | ACID ADDUCT SALTS OF SUBSTITUTED PYRIDINE COMPOUND AS CHOLESTERYL ESTER TRANSFER PROTEIN (CETP) INHIBITORS | DAIICHI SANKYO CO LTD (JP) | 2016-07-27 | — | — | EP | disclosed |
| US-9321747-B2 | Acid addition salt of substituted pyridine compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2016-04-26 | — | — | US | disclosed |
| US-20150299169-A1 | ACID ADDITION SALT OF SUBSTITUTED PYRIDINE COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2015-10-22 | — | — | US | disclosed |
| EP-2801574-A1 | ACID ADDUCT SALT OF SUBSTITUTED PYRIDINE COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2014-11-12 | — | — | EP | disclosed |
| US-8124780-B2 | Benzimidazole compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-02-28 | — | — | US | disclosed |
| CN-101160306-B | Benzimidazole compounds | EISAI R&D MAN CO LTD | 2011-11-02 | — | — | CN | disclosed |
| US-20090203911-A1 | BENZIMIDAZOLE COMPOUND | MIYAZAWA SHUHEI | 2009-08-13 | — | — | US | disclosed |
| US-7425634-B2 | Benzimidazole compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2008-09-16 | — | — | US | disclosed |
| EP-1870409-A1 | BENZIMIDAZOLE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2007-12-26 | — | — | EP | disclosed |
| WO-2007122686-A1 | BENZIMIDAZOLE COMPOUNDS | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2007-11-01 | — | — | WO | disclosed |
| US-20070015782-A1 | Benzimidazole compound | EISAI CO., LTD. | 2007-01-18 | — | — | US | disclosed |
| US-20070010542-A1 | Benzimidazole compound | EISAI CO., LTD. | 2007-01-11 | — | — | US | disclosed |
| WO-2006112442-A1 | BENZIMIDAZOLE COMPOUND | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2006-10-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010542-A1 | Benzimidazole compound | HRH2, GIPR, HRH4 | CA2 88/4885APP 4883/4885 |
| US-20150299169-A1 | ACID ADDITION SALT OF SUBSTITUTED PYRIDINE COMPOUND | CETP, SLC10A1, MTTP | CA2 251/4885APP 2323/4885 |
| US-20090203911-A1 | BENZIMIDAZOLE COMPOUND | HRH2, HRH4, HRH1 | CA2 60/4885APP 4879/4885 |
| US-20070015782-A1 | Benzimidazole compound | HRH2, GIPR, HRH4 | CA2 88/4885APP 4883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.