Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 3/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.50 |
| ▸ | F10 | P00742 | 2/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 4/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | C1S | P09871 | 1/20 | 0.46 |
| ▸ | ST14 | Q9Y5Y6 | 3/20 | 0.43 |
| ▸ | NQO2 | P16083 | 2/20 | 0.43 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | WDR5 | P61964 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MASP2 | O00187 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7450129 | 1.00 | PRSS1 (0.50) | PRSS1PRSS2PRSS3F10LOXL2 | |
| SCHEMBL8952285 | 1.00 | PRSS1 (0.50) | PRSS1PRSS2PRSS3F10LOXL2 | |
| SCHEMBL18520211 | 0.84 | TPH1 (0.37) | PRSS1PRSS2PRSS3F10LOXL2 | |
| SCHEMBL7176662 | 0.80 | PRSS1 (0.56) | PRSS1PRSS2PRSS3F10LOXL2 | |
| SCHEMBL7176658 | 0.80 | PRSS1 (0.56) | PRSS1PRSS2PRSS3F10LOXL2 | |
| SCHEMBL10077580 | 0.80 | ANPEP (0.59) | ALDH1A1 | |
| SCHEMBL10282665 | 0.79 | KMT2A (0.52) | ALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL1053349 | 0.79 | KMT2A (0.52) | ALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL5665191 | 0.78 | PRSS1 (0.35) | PRSS1PRSS2PRSS3F2PLG | |
| SCHEMBL20715008 | 0.78 | PRSS1 (0.35) | PRSS1PRSS2PRSS3F2PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760002-A | ANALGESICS | THE PROCTOR & GAMBLE COMPANY (US) | 1998-06-02 | — | — | US | claimed |
| US-5663297-A | OLIGOPEPTIDES | HOFFMANN-LA ROCHE INC. (US) | 1997-09-02 | — | — | US | claimed |
| EP-0675901-A1 | DIFLUORO-PENTAPEPTIDE DERIVATIVE ANTI-INFLAMMATORY AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1995-10-11 | — | — | EP | claimed |
| WO-1994014842-A1 | DIFLUORO-PENTAPEPTIDE DERIVATIVE ANTI-INFLAMMATORY AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1994-07-07 | — | — | WO | claimed |
| EP-1189929-B1 | FACTOR VIIA INHIBITORS | AVENTIS PHARMA GMBH (DE) | 2003-08-06 | — | — | EP | disclosed |
| US-6500803-B1 | Factor VIIa inhibitors | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-12-31 | — | — | US | disclosed |
| US-6432922-B1 | ANTITUMOR AGENTS; ANGIOGENESIS INHIBITORS | CORVAS INTERNATIONAL, INC. | 2002-08-13 | — | — | US | disclosed |
| EP-1189929-A2 | FACTOR VIIA INHIBITORS | Aventis Pharma Deutschland GmbH (DE) | 2002-03-27 | — | — | EP | disclosed |
| EP-1100814-A2 | INHIBITORS OF UROKINASE AND BLOOD VESSEL FORMATION | CORVAS INTERNATIONAL, INC. (US) | 2001-05-23 | — | — | EP | disclosed |
| US-6204384-B1 | THROMBIN INHIBITOR; ANTICOAGULANTS | CORVAS INTERNATIONAL, INC. | 2001-03-20 | — | — | US | disclosed |
| WO-2000075172-A2 | FACTOR VIIa INHIBITORS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-12-14 | — | — | WO | disclosed |
| EP-1059302-A1 | Factor VIIa inhibitors | Aventis Pharma Deutschland GmbH (DE) | 2000-12-13 | — | — | EP | disclosed |
| WO-2000005245-A2 | INHIBITORS OF UROKINASE AND BLOOD VESSEL FORMATION | CORVAS INTERNATIONAL, INC. (US) | 2000-02-03 | — | — | WO | disclosed |
| US-6011047-A | Substituted 3-amino-2-hydroxyphenylacetamide derivatives as enzyme inhibitors | CORVAS INTERNATIONAL INC. (US) | 2000-01-04 | — | — | US | disclosed |
| WO-1999026920-A1 | SUBSTITUTED 3-AMINO-2-HYDROXYPHENYLACETAMIDE DERIVATIVES AS ENZYME INHIBITORS (II) | CORVAS INTERNATIONAL, INC. (US) | 1999-06-03 | — | — | WO | disclosed |