⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8978214 | 0.97 | AOC3 (0.34) | — | |
| SCHEMBL22212766 | 0.89 | CA1 (0.43) | — | |
| SCHEMBL11251614 | 0.88 | — | — | |
| SCHEMBL28072446 | 0.88 | — | — | |
| SCHEMBL911346 | 0.87 | ALOX15 (0.33) | — | |
| SCHEMBL14530191 | 0.87 | OPRM1 (0.44) | — | |
| SCHEMBL11328681 | 0.85 | — | — | |
| SCHEMBL12124043 | 0.84 | OPRM1 (0.42) | — | |
| SCHEMBL7344683 | 0.84 | OPRM1 (0.42) | — | |
| SCHEMBL5393066 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295180-A1 | PROTEIN DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-09-21 | — | — | US | disclosed |
| WO-2017120194-A1 | PYRIDINE AND PYRIDIMINE COMPOUNDS AS PI3K-GAMMA INHIBITORS | INCYTE CORPORATION (US) | 2017-07-13 | — | — | WO | disclosed |
| CN-1127487-C | Phthalazinones | ALTANA PHARMA AG (DE) | 2003-11-12 | — | — | CN | disclosed |
| EP-0971901-B1 | PHTHALAZINONES | ALTANA PHARMA AG (DE) | 2003-02-26 | — | — | EP | disclosed |
| US-6103718-A | Phthalazinones | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2000-08-15 | — | — | US | disclosed |
| CN-1249749-A | Phthalazinones | BYK GULDEN LOMBERC CHEM FAB GM (DE) | 2000-04-05 | — | — | CN | disclosed |
| EP-0971901-A1 | PHTHALAZINONES | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 2000-01-19 | — | — | EP | disclosed |
| WO-1998031674-A1 | PHTHALAZINONES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1998-07-23 | — | — | WO | disclosed |