Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD5 | P21918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7176890 | 0.92 | MAPK1 (0.61) | SMN1; SMN2MAPK1L3MBTL1KDM1ACHRM2 | |
| SCHEMBL7177984 | 0.85 | MAPK1 (0.64) | SMN1; SMN2MAPK1L3MBTL1KDM1ACHRM2 | |
| SCHEMBL7142067 | 0.77 | MAPK1 (0.64) | SMN1; SMN2MAPK1L3MBTL1KDM1ACHRM2 | |
| SCHEMBL8709456 | 0.72 | MAPK1 (0.72) | SMN1; SMN2MAPK1L3MBTL1KDM1ACHRM2 | |
| SCHEMBL13921299 | 0.72 | MAPK1 (0.82) | SMN1; SMN2MAPK1L3MBTL1CHRM2CHRM4 | |
| SCHEMBL6988444 | 0.71 | SMN1; SMN2 (0.58) | SMN1; SMN2MAPK1L3MBTL1KDM1ACHRM2 | |
| SCHEMBL11204393 | 0.68 | MAPK1 (0.68) | SMN1; SMN2MAPK1L3MBTL1KDM1ACHRM2 | |
| SCHEMBL9039655 | 0.67 | MAPK1 (0.72) | SMN1; SMN2MAPK1L3MBTL1KDM1ACHRM2 | |
| SCHEMBL10409949 | 0.66 | MAPK1 (0.79) | SMN1; SMN2MAPK1L3MBTL1KDM1ACHRM2 | |
| SCHEMBL11521605 | 0.66 | MAPK1 (0.79) | SMN1; SMN2MAPK1L3MBTL1KDM1ACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675887-B1 | ANTIALLERGIC TRIAZOLOBENZAZEPINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2003-04-02 | — | — | EP | disclosed |