Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 8/20 | 0.55 |
| ▸ | THRB | P10828 | 8/20 | 0.55 |
| ▸ | RARB | P10826 | 5/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | RARA | P10276 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MTOR | P42345 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9504858 | 0.98 | THRA (0.57) | THRATHRBRARBTRPV1MEN1 | |
| SCHEMBL8115787 | 0.89 | ESR1 (0.54) | THRATHRBTRPV1KMT2AALDH1A1 | |
| SCHEMBL9504749 | 0.82 | THRA (0.59) | THRATHRBRARBTRPV1MEN1 | |
| SCHEMBL8429380 | 0.82 | MLYCD (0.53) | MEN1KMT2AALDH1A1MAPTMTOR | |
| SCHEMBL9504685 | 0.81 | THRA (0.61) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL9508248 | 0.81 | THRA (0.61) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL9504649 | 0.81 | THRA (0.61) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL9508189 | 0.81 | THRA (0.61) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL9504768 | 0.81 | THRA (0.61) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL9504888 | 0.81 | THRA (0.61) | THRATHRBRARBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6509367-B1 | Pyrazole cannabinoid agonist and antagonists | VIRGINIA COMMONWEALTH UNIVERSITY | 2003-01-21 | — | — | US | disclosed |