Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.64 |
| ▸ | MAOB | P27338 | 5/20 | 0.55 |
| ▸ | APP | P05067 | 3/20 | 0.55 |
| ▸ | OSBP | P22059 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.51 |
| ▸ | PTGES | O14684 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SI | P14410 | 1/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10494097 | 0.87 | OSBP (0.64) | BACE1MAOBAPPOSBPPTPN1 | |
| SCHEMBL10494091 | 0.87 | OSBP (0.64) | BACE1MAOBAPPOSBPPTPN1 | |
| SCHEMBL4614966 | 0.85 | BACE1 (0.79) | BACE1MAOBAPPOSBPPTPN1 | |
| SCHEMBL4807578 | 0.85 | BACE1 (0.79) | BACE1MAOBAPPOSBPPTPN1 | |
| SCHEMBL29352109 | 0.85 | BACE1 (0.79) | BACE1MAOBAPPOSBPPTPN1 | |
| SCHEMBL24075725 | 0.85 | OSBP (0.54) | BACE1MAOBAPPOSBPPTPN1 | |
| SCHEMBL28252730 | 0.85 | BACE1 (0.60) | BACE1MAOBAPPOSBPPTPN1 | |
| SCHEMBL30812628 | 0.82 | BACE1 (0.58) | BACE1MAOBAPPOSBPPTPN1 | |
| SCHEMBL7135772 | 0.82 | BACE1 (0.57) | BACE1MAOBAPPOSBPPTPN1 | |
| SCHEMBL24075562 | 0.81 | PTGES (0.57) | BACE1MAOBAPPOSBPPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003080844-A2 | ENHANCEMENT OF VITAMIN E CONTENT IN ORGANISMS BY ENHANCING 2-METHYL-6-PHYTYL HYDROQUINONE-METHYLTRANSFERASE ACTIVITY | SUNGENE GMBH & CO KGAA (DE) | 2003-10-02 | — | — | WO | disclosed |