Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 4/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.57 |
| ▸ | MAOB | P27338 | 6/20 | 0.54 |
| ▸ | APP | P05067 | 3/20 | 0.54 |
| ▸ | CNR1 | P21554 | 2/20 | 0.52 |
| ▸ | CNR2 | P34972 | 2/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.52 |
| ▸ | PTGES | O14684 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | OSBP | P22059 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.50 |
| ▸ | TRPM7 | Q96QT4 | 1/20 | 0.50 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | INHA | P05111 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9714237 | 0.92 | PTPN1 (0.61) | BACE1PTPN1MAOBAPPCNR1 | |
| SCHEMBL9714250 | 0.92 | PTPN1 (0.61) | BACE1PTPN1MAOBAPPCNR1 | |
| SCHEMBL7048803 | 0.86 | MAOB (0.63) | BACE1PTPN1MAOBAPPCNR1 | |
| SCHEMBL7080850 | 0.86 | MAOB (0.63) | BACE1PTPN1MAOBAPPCNR1 | |
| Cymopol SCHEMBL8649278 | 0.83 | BACE1 (0.52) | BACE1PTPN1MAOBAPPCNR1 | |
| Cymopol SCHEMBL21055681 | 0.83 | BACE1 (0.52) | BACE1PTPN1MAOBAPPCNR1 | |
| Cymopol SCHEMBL29378158 | 0.83 | BACE1 (0.52) | BACE1PTPN1MAOBAPPCNR1 | |
| SCHEMBL7140643 | 0.82 | BACE1 (0.64) | BACE1PTPN1MAOBAPPCNR1 | |
| SCHEMBL14248819 | 0.81 | MAOB (0.65) | BACE1PTPN1MAOBAPPCNR1 | |
| SCHEMBL15970570 | 0.81 | MAOB (0.65) | BACE1PTPN1MAOBAPPCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003080844-A2 | ENHANCEMENT OF VITAMIN E CONTENT IN ORGANISMS BY ENHANCING 2-METHYL-6-PHYTYL HYDROQUINONE-METHYLTRANSFERASE ACTIVITY | SUNGENE GMBH & CO KGAA (DE) | 2003-10-02 | — | — | WO | disclosed |