Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRG | P62508 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | CKS1B | P61024 | 1/20 | 0.32 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GLI1 | P08151 | 1/20 | 0.32 |
| ▸ | GLI2 | P10070 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7077392 | 0.94 | GLI1 (0.35) | ESRRGCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7140948 | 0.90 | LMNA (0.34) | ESRRGALOX15GLI1GLI2CA1 | |
| SCHEMBL6301693 | 0.85 | ESRRG (0.31) | ESRRGGLI1GLI2 | |
| SCHEMBL6297501 | 0.85 | GLI1 (0.35) | ESRRGGLI1GLI2ESR1ESR2 | |
| SCHEMBL6295877 | 0.85 | GLI1 (0.34) | ESRRGGLI1GLI2LMNASMN1; SMN2 | |
| SCHEMBL6297479 | 0.82 | ESRRG (0.32) | ESRRGGLI1GLI2 | |
| SCHEMBL6295744 | 0.82 | GLI1 (0.32) | ESRRGGLI1GLI2 | |
| SCHEMBL6295960 | 0.82 | GLI1 (0.32) | ESRRGGLI1GLI2 | |
| SCHEMBL7080698 | 0.81 | ESRRG (0.35) | ESRRGCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7077573 | 0.80 | CNR2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6512006-B1 | Novel 3-position Nitrogen substituted 6,6- disubstituted-5, 6-dihydropyrones and related compounds possess antiviral properties | WARNER-LAMBERT COMPANY | 2003-01-28 | — | — | US | claimed |