Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | GLI1 | P08151 | 1/20 | 0.32 |
| ▸ | GLI2 | P10070 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 2/20 | 0.31 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ESRRG | P62508 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7140943 | 0.90 | ESRRG (0.34) | LMNAGLI1GLI2CA1CA2 | |
| SCHEMBL7077392 | 0.83 | GLI1 (0.35) | LMNAGLI1GLI2CA1CA2 | |
| SCHEMBL6295877 | 0.83 | GLI1 (0.34) | LMNAGLI1GLI2ESR1ESRRG | |
| SCHEMBL6301693 | 0.82 | ESRRG (0.31) | GLI1GLI2ESRRG | |
| SCHEMBL6297501 | 0.82 | GLI1 (0.35) | GLI1GLI2ESR1ESR2ESRRG | |
| SCHEMBL6295744 | 0.79 | GLI1 (0.32) | GLI1GLI2ESRRG | |
| SCHEMBL6297479 | 0.79 | ESRRG (0.32) | GLI1GLI2ESRRG | |
| SCHEMBL6295960 | 0.79 | GLI1 (0.32) | GLI1GLI2ESRRG | |
| SCHEMBL7141092 | 0.79 | WRN (0.33) | DRD2DRD3 | |
| SCHEMBL6295927 | 0.78 | ESR1 (0.36) | LMNADRD2DRD3GLI1GLI2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6512006-B1 | Novel 3-position Nitrogen substituted 6,6- disubstituted-5, 6-dihydropyrones and related compounds possess antiviral properties | WARNER-LAMBERT COMPANY | 2003-01-28 | — | — | US | claimed |