Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WRN | Q14191 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | MLNR | O43193 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | PGA5 | P0DJD9 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | CTSE | P14091 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6295877 | 0.95 | GLI1 (0.34) | OPRD1OPRM1OPRK1 | |
| SCHEMBL6295721 | 0.93 | PPIB (0.32) | DRD2DRD1 | |
| SCHEMBL7078899 | 0.92 | WRN (0.34) | WRNGAAL3MBTL1OPRD1OPRM1 | |
| SCHEMBL6297393 | 0.91 | OPRD1 (0.32) | OPRD1DRD2OPRM1DRD3OPRK1 | |
| SCHEMBL6296998 | 0.90 | DRD2 (0.35) | OPRD1DRD2OPRM1DRD3OPRK1 | |
| SCHEMBL6295927 | 0.89 | ESR1 (0.36) | OPRD1DRD2OPRM1DRD3OPRK1 | |
| SCHEMBL6297392 | 0.88 | OPRM1 (0.34) | OPRD1DRD2OPRM1DRD3OPRK1 | |
| SCHEMBL6297136 | 0.88 | HTR1A (0.30) | — | |
| SCHEMBL7078065 | 0.88 | WRN (0.36) | WRNGAAL3MBTL1OPRD1OPRM1 | |
| SCHEMBL6301730 | 0.87 | TRPM8 (0.42) | GAADRD2OPRM1DRD3OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6512006-B1 | Novel 3-position Nitrogen substituted 6,6- disubstituted-5, 6-dihydropyrones and related compounds possess antiviral properties | WARNER-LAMBERT COMPANY | 2003-01-28 | — | — | US | claimed |