SCHEMBL7141129

SCHEMBL7141129

C[n+]1ccc(S)cc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Paraquat SCHEMBL4895671 0.72 SLC6A4 (0.77)
Paraquat SCHEMBL21652 0.72 SLC6A4 (0.77)
Paraquat SCHEMBL9650240 0.69 SLC6A4 (0.72)
Paraquat SCHEMBL22370108 0.69 SLC6A4 (0.72)
Paraquat SCHEMBL11281521 0.69 SLC6A4 (0.72)
Paraquat SCHEMBL8677067 0.69 SLC6A4 (0.72)
SCHEMBL14596518 0.69 SLC6A4 (0.72)
Paraquat SCHEMBL21653 0.69 SLC6A4 (0.72)
SCHEMBL80079 0.69
Paraquat SCHEMBL8331549 0.69 SLC6A4 (0.72)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0153709-A2 Novel cephalosporin derivatives MEIJI SEIKA KAISHA LTD. (JP) 1985-09-04 EP claimed
EP-1086124-B1 NOVEL CYCLOSPORINS CHEM AG C (CH) 2003-11-19 EP disclosed
EP-0892805-B1 PRODUCTION OF 7-AMINOCEPHALOSPORANIC ACID DERIVATIVE TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2003-07-02 EP disclosed
US-6583265-B1 Compound for use in the prevention of viral and bacterial infections C-CHEM AG (CH) 2003-06-24 US disclosed
EP-0892805-A1 PRODUCTION OF 7-AMINOCEPHALOSPORANIC ACID DERIVATIVE Takeda Chemical Industries, Ltd. (JP) 1999-01-27 EP disclosed
WO-1997039002-A1 PRODUCTION OF 7-AMINOCEPHALOSPORANIC ACID DERIVATIVE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1997-10-23 WO disclosed