Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | CDC25B | P30305 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6001659 | 0.84 | ALDH1A1 (0.70) | HSD17B10ALDH1A1TSHRCDC25BMAPT | |
| SCHEMBL17194998 | 0.83 | ALDH1A1 (0.68) | HSD17B10ALDH1A1TSHRCDC25BMAPT | |
| Ethyl Anthranilate SCHEMBL28379679 | 0.80 | HSD17B10 (0.84) | HSD17B10ALDH1A1TSHRCDC25BKMT2A | |
| SCHEMBL16401931 | 0.78 | HSD17B10 (0.60) | HSD17B10ALDH1A1TSHRCDC25BMAPT | |
| SCHEMBL2925689 | 0.78 | ALDH1A1 (0.74) | HSD17B10ALDH1A1TSHRCDC25BMAPT | |
| SCHEMBL717606 | 0.78 | ALDH1A1 (0.74) | HSD17B10ALDH1A1TSHRCDC25BMAPT | |
| Ethyl Anthranilate SCHEMBL30055126 | 0.77 | ALDH1A1 (1.00) | HSD17B10ALDH1A1TSHRCDC25BMAPT | |
| Ethyl Anthranilate SCHEMBL34474 | 0.77 | ALDH1A1 (1.00) | HSD17B10ALDH1A1TSHRCDC25BMAPT | |
| SCHEMBL2894636 | 0.76 | ALDH1A1 (0.72) | HSD17B10ALDH1A1TSHRCDC25BMAPT | |
| SCHEMBL177310 | 0.76 | ALDH1A1 (0.72) | HSD17B10ALDH1A1TSHRCDC25BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2786153-B1 | ISOTOPIC LABELING OF HIGHER ORGANISMS | SILANTES GMBH (DE) | 2019-01-09 | — | — | EP | disclosed |
| US-20140328760-A1 | ISOTOPIC LABELING OF HIGHER ORGANISMS | SILANTES GMBH (DE) | 2014-11-06 | — | — | US | disclosed |
| EP-2786153-A1 | ISOTOPIC LABELING OF HIGHER ORGANISMS | Silantes GmbH (DE) | 2014-10-08 | — | — | EP | disclosed |
| WO-2013079558-A1 | ISOTOPIC LABELING OF HIGHER ORGANISMS | SILANTES GMBH (DE) | 2013-06-06 | — | — | WO | disclosed |
| EP-1303485-A1 | PYRROLIDINE DERIVATIVES AS INHIBITORS OF ENDOTHELIN-CONVERTING ENZYME | F. HOFFMANN-LA ROCHE AG (CH) | 2003-04-23 | — | — | EP | disclosed |
| US-20020049243-A1 | Pyrrolidine derivatives | HOFFMANN-LA ROCHE INC. | 2002-04-25 | — | — | US | disclosed |
| WO-2002006222-A1 | PYRROLIDINE DERIVATIVES AS INHIBITORS OF ENDOTHELIN-CONVERTING ENZYME | F. HOFFMANN-LA ROCHE AG (CH) | 2002-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020049243-A1 | Pyrrolidine derivatives | PREP, PEPD, DNPEP | HSD17B10 799/4885ALDH1A1 767/4885TSHR 2814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.