Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylamine SCHEMBL7141650 | 0.72 | ADORA3 (0.42) | GBA1 | |
| SCHEMBL6776176 | 0.71 | SRC (0.37) | EGFR | |
| SCHEMBL7141657 | 0.70 | HDAC4 (0.34) | EGFRGBA1 | |
| SCHEMBL6775465 | 0.66 | KDM4E (0.30) | — | |
| SCHEMBL2010330 | 0.61 | EGFR (0.55) | EGFR | |
| SCHEMBL738516 | 0.58 | EGFR (0.55) | EGFR | |
| SCHEMBL27557205 | 0.58 | EGFR (0.55) | EGFR | |
| SCHEMBL5077890 | 0.58 | EGFR (0.51) | EGFR | |
| SCHEMBL7682831 | 0.56 | FFAR1 (0.41) | — | |
| SCHEMBL7959593 | 0.56 | EGFR (0.51) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272185-A2 | USE OF QUINAZOLINE DERIVATIVES AS ANGIOGENESIS INHIBITORS | AstraZeneca AB (SE) | 2003-01-08 | — | — | EP | disclosed |
| WO-2001066099-A2 | USE OF QUINAZOLINE DERIVATIVES AS ANGIOGENESIS INHIBITORS | ASTRAZENECA AB (SE) | 2001-09-13 | — | — | WO | disclosed |