Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 11/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.30 |
| ▸ | FEN1 | P39748 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6319426 | 0.92 | PTGS2 (0.49) | PTGS2PTGS1 | |
| SCHEMBL6315057 | 0.81 | PTGS2 (0.55) | PTGS2PTGS1 | |
| Hydrochloric Acid SCHEMBL6322201 | 0.80 | PTGS2 (0.55) | PTGS2PTGS1 | |
| SCHEMBL6316399 | 0.80 | PTGS2 (0.48) | PTGS2PTGS1ALOX5APFEN1 | |
| SCHEMBL6314404 | 0.77 | PTGS2 (0.54) | PTGS2PTGS1 | |
| SCHEMBL6315488 | 0.72 | PTGS2 (0.60) | PTGS2PTGS1 | |
| SCHEMBL6315912 | 0.71 | PTGS2 (0.48) | PTGS2PTGS1 | |
| SCHEMBL6314675 | 0.71 | PTGS2 (0.55) | PTGS2PTGS1 | |
| SCHEMBL6313914 | 0.71 | PTGS2 (0.50) | PTGS2PTGS1 | |
| Hydrochloric Acid SCHEMBL6317049 | 0.70 | PTGS2 (0.49) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030144280-A1 | Sulfamoylheteroaryl pyrazole compounds as anti-inflammatory/analgesic agents | PFIZER INC. (US) | 2003-07-31 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144280-A1 | Sulfamoylheteroaryl pyrazole compounds as anti-inflammatory/analgesic agents | PTGS1, PTGS2, SULT2A1 | PTGS2 2/4885PTGS1 1/4885ALOX5AP 271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.