Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.79 |
| ▸ | NPC1 | O15118 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.65 |
| ▸ | RAB9A | P51151 | 2/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | MYOC | Q99972 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | CA12 | O43570 | 2/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.59 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | CA9 | Q16790 | 2/20 | 0.59 |
| ▸ | PTGES | O14684 | 1/20 | 0.58 |
| ▸ | TGM2 | P21980 | 1/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | NAMPT | P43490 | 1/20 | 0.56 |
| ▸ | MITF | O75030 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8530544 | 0.98 | MEN1 (0.76) | MEN1KMT2ANPC1MAPTMAPK1 | |
| SCHEMBL11837944 | 0.91 | MEN1 (0.82) | MEN1KMT2ANPC1MAPTMAPK1 | |
| SCHEMBL6302157 | 0.88 | MEN1 (1.00) | MEN1KMT2ANPC1MAPTMAPK1 | |
| SCHEMBL1177730 | 0.88 | MEN1 (1.00) | MEN1KMT2ANPC1MAPTMAPK1 | |
| SCHEMBL1311708 | 0.84 | MEN1 (0.82) | MEN1KMT2ANPC1MAPTMAPK1 | |
| SCHEMBL16005844 | 0.83 | MEN1 (0.81) | MEN1KMT2ANPC1MAPTMAPK1 | |
| SCHEMBL6302417 | 0.83 | MEN1 (0.89) | MEN1KMT2ANPC1MAPTMAPK1 | |
| SCHEMBL6939392 | 0.82 | MEN1 (0.79) | MEN1KMT2ANPC1MAPTMAPK1 | |
| SCHEMBL6465464 | 0.81 | MEN1 (0.79) | MEN1KMT2ANPC1MAPTMAPK1 | |
| SCHEMBL9285904 | 0.81 | MEN1 (0.79) | MEN1KMT2ANPC1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108558756-B | 2-aryl-2, 3-dihydro-4 (1H) -quinolinone semicarbazone compound and application thereof | 沈阳药科大学 | 2021-08-03 | — | — | CN | disclosed |
| EP-1140917-B1 | S-OXIDE LIPID LOWERING COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2003-03-26 | — | — | EP | disclosed |
| US-6451802-B1 | S-oxide lipid lowering compounds | JANSSEN PHARMACEUTICA N.V. (BE) | 2002-09-17 | — | — | US | disclosed |
| EP-1140917-A1 | S-OXIDE LIPID LOWERING COMPOUNDS | JANSSEN PHARMACEUTICA N.V. (BE) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000037463-A1 | S-OXIDE LIPID LOWERING COMPOUNDS | JANSSEN PHARMACEUTICA N.V. (BE) | 2000-06-29 | — | — | WO | disclosed |
| EP-0646574-B1 | Ketonic indane derivatives, their preparation and therapeutic application thereof | INNOTHERA LAB SA (FR) | 1998-12-09 | — | — | EP | disclosed |
| EP-0474817-B1 | BICYCLO [3.3.0]OCTANE DERIVATIVES, PROCESS FOR PRODUCING THEM AND THEIR PHARMACEUTICAL USE | SCHERING AG (DE) | 1995-10-11 | — | — | EP | disclosed |
| EP-0646574-A1 | Ketonic indane derivatives, their preparation and therapeutic application thereof | LABORATOIRE INNOTHERA Société Anonyme (FR) | 1995-04-05 | — | — | EP | disclosed |
| EP-0474817-A1 | BICYCLO 3.3.)]OCTANE DERIVATIVES, PROCESS FOR PRODUCING THEM AND THEIR PHARMACEUTICAL USE. | SCHERING AG (DE) | 1992-03-18 | — | — | EP | disclosed |
| WO-1991014675-A1 | BICYCLO[3.3.)]OCTANE DERIVATIVES, PROCESS FOR PRODUCING THEM AND THEIR PHARMACEUTICAL USE | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1991-10-03 | — | — | WO | disclosed |
| US-4490530-A | ANTIFUNGAL, ANTIBACTERIAL | JANSSEN PHARMACEUTICA N.V. (BE) | 1984-12-25 | — | — | US | disclosed |
| EP-0006711-B1 | HETEROCYCLIC DERIVATIVES OF (4-PHENYLPIPERAZIN-1-YL-ARYLOXYMETHYL-1,3-DIOXOLAN-2-YL)-METHYL-1H-IMIDAZOLES AND 1H-1,2,4-TRIAZOLES, PROCESSES FOR PREPARING THEM AND COMPOSITIONS CONTAINING THEM | JANSSEN PHARMACEUTICA N.V. (BE) | 1983-10-26 | — | — | EP | disclosed |
| US-4368200-A | BACTERICIDES, FUNGICIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 1983-01-11 | — | — | US | disclosed |
| US-4267179-A | AS FUNGICIDES AND BACTERICIDES | JANSSEN PHARMACEUTICA, N.V. (BE) | 1981-05-12 | — | — | US | disclosed |
| EP-0006711-A1 | Heterocyclic derivatives of (4-phenylpiperazin-1-yl-aryloxymethyl-1,3-dioxolan-2-yl)-methyl-1H-imidazoles and 1H-1,2,4-triazoles, processes for preparing them and compositions containing them | JANSSEN PHARMACEUTICA N.V. (BE) | 1980-01-09 | — | — | EP | disclosed |