Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.79 |
| ▸ | NPC1 | O15118 | 5/20 | 0.65 |
| ▸ | RAB9A | P51151 | 4/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | MYOC | Q99972 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | PTGES | O14684 | 1/20 | 0.58 |
| ▸ | TGM2 | P21980 | 1/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | NAMPT | P43490 | 1/20 | 0.56 |
| ▸ | MITF | O75030 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6302157 | 0.88 | MEN1 (1.00) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL1177730 | 0.88 | MEN1 (1.00) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL6302417 | 0.83 | MEN1 (0.89) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL16005844 | 0.83 | MEN1 (0.81) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL9285911 | 0.81 | KMT2A (0.79) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL9285904 | 0.81 | MEN1 (0.79) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL11055960 | 0.81 | MEN1 (0.85) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL7142294 | 0.81 | MEN1 (0.79) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL8848976 | 0.81 | KMT2A (0.71) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL1311708 | 0.80 | MEN1 (0.82) | MEN1KMT2ANPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1148048-B1 | Polyaromatic compounds for treating herpes viral infections | PHARMACIA & UPJOHN CO LLC (US) | 2005-06-29 | — | — | EP | claimed |