SCHEMBL714234

SCHEMBL714234

C[C@H](Nc1ccccc1F)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.66
LMNA P02545 2/20 0.66
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
GAA P10253 3/20 0.48
ALDH1A1 P00352 3/20 0.47
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
HPGD P15428 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29665643 1.00 SMN1; SMN2 (0.66) SMN1; SMN2LMNAMEN1KMT2ANPC1
SCHEMBL714235 1.00 SMN1; SMN2 (0.66) SMN1; SMN2LMNAMEN1KMT2ANPC1
SCHEMBL17260383 0.86 SMN1; SMN2 (0.54) SMN1; SMN2LMNAMEN1KMT2ANPC1
SCHEMBL17646176 0.86 SMN1; SMN2 (0.54) SMN1; SMN2LMNAMEN1KMT2ANPC1
SCHEMBL30317493 0.84 MEN1 (0.53) SMN1; SMN2LMNAMEN1KMT2ANPC1
Hydrochloric Acid SCHEMBL30317257 0.82 MEN1 (0.51) SMN1; SMN2LMNAMEN1KMT2ANPC1
SCHEMBL11202529 0.82 SMN1; SMN2 (0.54) SMN1; SMN2LMNAMEN1KMT2ANPC1
SCHEMBL11202526 0.82 SMN1; SMN2 (0.54) SMN1; SMN2LMNAMEN1KMT2ANPC1
SCHEMBL21635122 0.82 SMN1; SMN2 (0.62) SMN1; SMN2LMNAMEN1KMT2ANPC1
Hydrochloric Acid SCHEMBL16059705 0.81 MEN1 (0.66) SMN1; SMN2LMNAMEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2084182-B1 ANTIDIABETIC COMPOUNDS CADILA HEALTHCARE LTD (IN) 2013-08-28 EP claimed
EP-0808838-B1 Sulfur-containing heterocyclic bradykinin antagonists, processes for their production and use thereof HOECHST AG (DE) 2003-10-22 EP claimed
JP-6189694-A None JP disclosed
WO-2025262023-A1 PROTEIN OLIGOMERS FOR ACTIVE IMMUNIZATION HEIDELBERG BIOTECH GMBH (DE) 2025-12-26 WO disclosed
WO-2025262082-A1 UNIVERSAL PRINCIPLES OF ACTIVE AND PASSIVE IMMUNIZATION AGAINST VIRAL ANTIGENS HEIDELBERG BIOTECH GMBH (DE) 2025-12-26 WO disclosed
WO-2025262025-A1 PHARMACEUTICAL COMPOSITION FOR PASSIVE IMMUNIZATION OR THERAPY HEIDELBERG BIOTECH GMBH (DE) 2025-12-26 WO disclosed
US-12428455-B2 Dominant negative CEBPB and CEBPD proteins and methods of use for decreasing viability of neoplastic cells THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2025-09-30 US disclosed
US-20250223328-A1 TRUNCATED DOMINANT NEGATIVE CEBPB AND CEBPD PROTEINS AND METHODS OF USE FOR DECREASING VIABILITY OF NEOPLASTIC CELLS THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK 2025-07-10 US disclosed
CN-113396218-B Engineered transaminase polypeptides 科德克希思公司 2025-02-18 CN disclosed
WO-2024086775-A2 TRUNCATED DOMINANT NEGATIVE CEBPB AND CEBPD PROTEINS AND METHODS OF USE FOR DECREASING VIABILITY OF NEOPLASTIC CELLS THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2024-04-25 WO disclosed
US-11746127-B2 Coronaviruses epitope-based vaccines RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2023-09-05 US disclosed
WO-1998024780-A2 SUBSTITUTED PYRIMIDINONE AND PYRIDINONE COMPOUNDS AND THEIR USE AMGEN INC. (US) 1998-06-11 WO disclosed
EP-0787116-A1 PROCESS FOR SEPARATING ENANTIOMERS FROM A RACEMIC MIXTURE Akzo Nobel N.V. (NL) 1997-08-06 EP disclosed
EP-0663897-B1 PROCESS FOR SEPARATING ENANTIOMERS FROM A RACEMIC MIXTURE AKZO NOBEL NV (NL) 1997-01-29 EP disclosed
US-5514773-A PARASITICIDES, ANTHELMINTICS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1996-05-07 US disclosed
WO-1996011894-A1 PROCESS FOR SEPARATING ENANTIOMERS FROM A RACEMIC MIXTURE AKZO NOBEL N.V. (NL) 1996-04-25 WO disclosed
EP-0663897-A1 PROCESS FOR SEPARATING ENANTIOMERS FROM A RACEMIC MIXTURE. AKZO NOBEL NV (NL) 1995-07-26 EP disclosed
EP-0634408-A1 DEPSIPEPTIDE DERIVATIVE, PRODUCTION THEREOF AND USE THEREOF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1995-01-18 EP disclosed
JP-H06189694-A PRODUCTION OF FOOD AND DRINK KYOWA HAKKO KOGYO CO LTD 1994-07-12 JP disclosed
WO-1994007814-A1 PROCESS FOR SEPARATING ENANTIOMERS FROM A RACEMIC MIXTURE AKZO NOBEL N.V. (NL) 1994-04-14 WO disclosed