SCHEMBL714235

SCHEMBL714235

CC(Nc1ccccc1F)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.66
LMNA P02545 2/20 0.66
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
GAA P10253 3/20 0.48
ALDH1A1 P00352 3/20 0.47
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
HPGD P15428 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29665643 1.00 SMN1; SMN2 (0.66) SMN1; SMN2LMNAMEN1KMT2ANPC1
SCHEMBL714234 1.00 SMN1; SMN2 (0.66) SMN1; SMN2LMNAMEN1KMT2ANPC1
SCHEMBL17260383 0.86 SMN1; SMN2 (0.54) SMN1; SMN2LMNAMEN1KMT2ANPC1
SCHEMBL17646176 0.86 SMN1; SMN2 (0.54) SMN1; SMN2LMNAMEN1KMT2ANPC1
SCHEMBL30317493 0.84 MEN1 (0.53) SMN1; SMN2LMNAMEN1KMT2ANPC1
Hydrochloric Acid SCHEMBL30317257 0.82 MEN1 (0.51) SMN1; SMN2LMNAMEN1KMT2ANPC1
SCHEMBL11202529 0.82 SMN1; SMN2 (0.54) SMN1; SMN2LMNAMEN1KMT2ANPC1
SCHEMBL11202526 0.82 SMN1; SMN2 (0.54) SMN1; SMN2LMNAMEN1KMT2ANPC1
SCHEMBL21635122 0.82 SMN1; SMN2 (0.62) SMN1; SMN2LMNAMEN1KMT2ANPC1
Hydrochloric Acid SCHEMBL16059705 0.81 MEN1 (0.66) SMN1; SMN2LMNAMEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2011518179-A 2011-06-23 JP claimed
EP-2279200-A1 BIOLOGICALLY ACTIVE PEPTIDES Baxter International Inc. (US) 2011-02-02 EP claimed
WO-2009137256-A1 BIOLOGICALLY ACTIVE PEPTIDES BAXTER INTERNATIONAL INC. (US) 2009-11-12 WO claimed
EP-0808838-B1 Sulfur-containing heterocyclic bradykinin antagonists, processes for their production and use thereof HOECHST AG (DE) 2003-10-22 EP claimed
CN-1112125-A Acyloxyhexanoic acid derivatives CIBA GEIGY AG (CH) 1995-11-22 CN claimed
JP-3160985-A None JP disclosed
JP-6189694-A None JP disclosed
WO-2025262082-A1 UNIVERSAL PRINCIPLES OF ACTIVE AND PASSIVE IMMUNIZATION AGAINST VIRAL ANTIGENS HEIDELBERG BIOTECH GMBH (DE) 2025-12-26 WO disclosed
WO-2025262023-A1 PROTEIN OLIGOMERS FOR ACTIVE IMMUNIZATION HEIDELBERG BIOTECH GMBH (DE) 2025-12-26 WO disclosed
WO-2025262025-A1 PHARMACEUTICAL COMPOSITION FOR PASSIVE IMMUNIZATION OR THERAPY HEIDELBERG BIOTECH GMBH (DE) 2025-12-26 WO disclosed
US-20250367263-A9 Therapeutic Regimens and Methods for Treatment of Cardiovascular Risk Factors using a GLP-1R and GCGR Agonist SPITFIRE PHARMA LLC (US) 2025-12-04 US disclosed
US-12428455-B2 Dominant negative CEBPB and CEBPD proteins and methods of use for decreasing viability of neoplastic cells THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2025-09-30 US disclosed
WO-1996011894-A1 PROCESS FOR SEPARATING ENANTIOMERS FROM A RACEMIC MIXTURE AKZO NOBEL N.V. (NL) 1996-04-25 WO disclosed
CN-1112125-A Acyloxyhexanoic acid derivatives CIBA GEIGY AG (CH) 1995-11-22 CN disclosed
EP-0663897-A1 PROCESS FOR SEPARATING ENANTIOMERS FROM A RACEMIC MIXTURE. AKZO NOBEL NV (NL) 1995-07-26 EP disclosed
EP-0634408-A1 DEPSIPEPTIDE DERIVATIVE, PRODUCTION THEREOF AND USE THEREOF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1995-01-18 EP disclosed
JP-H06189694-A PRODUCTION OF FOOD AND DRINK KYOWA HAKKO KOGYO CO LTD 1994-07-12 JP disclosed
WO-1994007814-A1 PROCESS FOR SEPARATING ENANTIOMERS FROM A RACEMIC MIXTURE AKZO NOBEL N.V. (NL) 1994-04-14 WO disclosed
JP-H03160985-A NOVEL VARIANT AND PREPARATION OF SOY SAUCE USING THEREOF KIKKOMAN CORP 1991-07-10 JP disclosed
EP-0331404-A2 Method for producing tropane alkaloid SEITAIKINOU RIYOU KAGAKUHIN SHINSEIZOUGIJUTSU KENKYU KUMIAI (JP) 1989-09-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250367263-A9 Therapeutic Regimens and Methods for Treatment of Cardiovascular Risk Factors using a GLP-1R and GCGR Agonist GLP1R, GCGR, GIPR SMN1; SMN2 3472/4885LMNA 2458/4885MEN1 1818/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.