SCHEMBL29665643

SCHEMBL29665643

C[C@H](Nc1ccccc1F)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.66
LMNA P02545 2/20 0.66
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
GAA P10253 3/20 0.48
ALDH1A1 P00352 3/20 0.47
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
HPGD P15428 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL714235 1.00 SMN1; SMN2 (0.66) SMN1; SMN2LMNAMEN1KMT2ANPC1
SCHEMBL714234 1.00 SMN1; SMN2 (0.66) SMN1; SMN2LMNAMEN1KMT2ANPC1
SCHEMBL17260383 0.86 SMN1; SMN2 (0.54) SMN1; SMN2LMNAMEN1KMT2ANPC1
SCHEMBL17646176 0.86 SMN1; SMN2 (0.54) SMN1; SMN2LMNAMEN1KMT2ANPC1
SCHEMBL30317493 0.84 MEN1 (0.53) SMN1; SMN2LMNAMEN1KMT2ANPC1
Hydrochloric Acid SCHEMBL30317257 0.82 MEN1 (0.51) SMN1; SMN2LMNAMEN1KMT2ANPC1
SCHEMBL11202529 0.82 SMN1; SMN2 (0.54) SMN1; SMN2LMNAMEN1KMT2ANPC1
SCHEMBL11202526 0.82 SMN1; SMN2 (0.54) SMN1; SMN2LMNAMEN1KMT2ANPC1
SCHEMBL21635122 0.82 SMN1; SMN2 (0.62) SMN1; SMN2LMNAMEN1KMT2ANPC1
Hydrochloric Acid SCHEMBL16059705 0.81 MEN1 (0.66) SMN1; SMN2LMNAMEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122094701-A TLR3 binding bicyclic peptide ligands 2026-05-26 CN claimed
US-12630588-B2 Bicyclic peptide ligands specific for CD137 BICYCLETX LIMITED (GB) 2026-05-19 US claimed
US-12551535-B2 Peptide pharmaceuticals for insulin resistance MEDERIS DIABETES, LLC (US) 2026-02-17 US claimed
US-20250325672-A1 ANTI-INFECTIVE BICYCLIC PEPTIDE LIGANDS BICYCLE TX LTD (GB) 2025-10-23 US claimed
US-20250296959-A1 B7-H3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF MARIANA ONCOLOGY INC (US) 2025-09-25 US claimed
WO-2025046244-A1 TLR3 BINDING BICYCLIC PEPTIDE LIGANDS BICYCLETX LIMITED (GB) 2025-03-06 WO claimed
US-20250059236-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR CD137 BICYCLETX LIMITED (GB) 2025-02-20 US claimed
US-20240424062-A1 PEPTIDE PHARMACEUTICALS FOR INSULIN RESISTANCE MEDERIS DIABETES LLC (US) 2024-12-26 US claimed
CN-118772242-A CD137 specific bicyclic peptide ligands 拜斯科技术开发有限公司 2024-10-15 CN claimed
US-12049520-B2 Bicyclic peptide ligands specific for CD137 BICYCLETX LIMITED (GB) 2024-07-30 US claimed
EP-4093757-A1 GIP/GLP1 CO-AGONIST COMPOUNDS Eli Lilly and Company (US) 2022-11-30 EP claimed
US-20220362345-A1 PEPTIDE PHARMACEUTICALS FOR INSULIN RESISTANCE MEDERIS DIABETES LLC (US) 2022-11-17 US claimed
CN-115298207-A GIP/GLP1 co-agonist compounds 伊莱利利公司 2022-11-04 CN claimed
WO-2022195287-A9 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR TREM2 BICYCLETX LIMITED (GB) 2022-10-20 WO claimed
US-20220296726-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR TREM2 BICYCLETX LIMITED (GB) 2022-09-22 US claimed
WO-2022195287-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR TREM2 BICYCLETX LIMITED (GB) 2022-09-22 WO claimed
WO-2022177744-A1 GIP/GLP1 DUAL AGONIST THERAPEUTIC METHODS ELI LILLY AND COMPANY (US) 2022-08-25 WO claimed
WO-2022148968-A1 ANTI-INFECTIVE BICYCLIC PEPTIDE LIGANDS BICYCLETX LIMITED (GB) 2022-07-14 WO claimed
US-20220213145-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR CD137 BICYCLETX LIMITED (GB) 2022-07-07 US claimed
EP-3661948-B1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR CD137 BICYCLETX LTD (GB) 2022-06-01 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250325672-A1 ANTI-INFECTIVE BICYCLIC PEPTIDE LIGANDS ACE2, SARS1, TMPRSS2 SMN1; SMN2 4777/4885LMNA 2785/4885MEN1 4373/4885
US-12630588-B2 Bicyclic peptide ligands specific for CD137 PTMS, IL36G, HLA-A SMN1; SMN2 4497/4885LMNA 452/4885MEN1 4195/4885
US-12551535-B2 Peptide pharmaceuticals for insulin resistance IAPP, GLP1R, INSR SMN1; SMN2 3910/4885LMNA 1547/4885MEN1 2329/4885
US-20240424062-A1 PEPTIDE PHARMACEUTICALS FOR INSULIN RESISTANCE IAPP, GLP1R, PTMS SMN1; SMN2 2670/4885LMNA 3205/4885MEN1 1876/4885
US-20250296959-A1 B7-H3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF CD274, CD44, CD74 SMN1; SMN2 3264/4885LMNA 3408/4885MEN1 640/4885
US-20220296726-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR TREM2 APP, TIMCC, ADM2 SMN1; SMN2 1109/4885LMNA 1950/4885MEN1 2147/4885
US-20250059236-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR CD137 CD2BP2, CD40, SDC1 SMN1; SMN2 3096/4885LMNA 2538/4885MEN1 3732/4885
US-20220362345-A1 PEPTIDE PHARMACEUTICALS FOR INSULIN RESISTANCE IAPP, GLP1R, PTMS SMN1; SMN2 2670/4885LMNA 3205/4885MEN1 1876/4885
US-20220213145-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR CD137 CD2BP2, CD40, SDC1 SMN1; SMN2 3096/4885LMNA 2538/4885MEN1 3732/4885
US-12049520-B2 Bicyclic peptide ligands specific for CD137 CD2BP2, CD40, SDC1 SMN1; SMN2 3096/4885LMNA 2538/4885MEN1 3732/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.