Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6745578 | 0.87 | ICAM1 (0.55) | ICAM1VCAM1 | |
| SCHEMBL6745585 | 0.87 | ICAM1 (0.55) | ICAM1VCAM1 | |
| SCHEMBL6747635 | 0.81 | ALOX5 (0.48) | ICAM1 | |
| SCHEMBL7142389 | 0.81 | ICAM1 (0.53) | ICAM1VCAM1 | |
| SCHEMBL6750349 | 0.76 | ICAM1 (0.59) | ICAM1VCAM1 | |
| SCHEMBL20558910 | 0.74 | OPRD1 (0.48) | — | |
| SCHEMBL7148828 | 0.72 | ICAM1 (0.60) | ICAM1VCAM1 | |
| SCHEMBL15765005 | 0.70 | CA12 (0.44) | — | |
| SCHEMBL7037888 | 0.70 | ICAM1 (0.76) | ICAM1VCAM1 | |
| SCHEMBL6745844 | 0.70 | ICAM1 (0.47) | ICAM1VCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518423-B1 | These compounds are useful as drugs efficacious in the prevention and treatment of these various inflammatory diseases and immunologic diseases, such as rheumatoid arthritis, atopic dermatitis, psoriasis, asthma, and | EISAI CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |