Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 8/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 11/20 | 0.36 |
| ▸ | THRA | P10827 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6453803 | 0.90 | P2RX7 (0.39) | P2RX7MEN1NR1I2KMT2AABCB11 | |
| SCHEMBL6455333 | 0.89 | P2RX7 (0.42) | P2RX7MEN1NR1I2KMT2AABCB11 | |
| SCHEMBL5762275 | 0.88 | KDM4E (0.43) | P2RX7MEN1KMT2AABCB11THRB | |
| SCHEMBL6462050 | 0.87 | P2RX7 (0.41) | P2RX7MEN1NR1I2KMT2AABCB11 | |
| SCHEMBL6462754 | 0.86 | P2RX7 (0.41) | P2RX7MEN1NR1I2KMT2AABCB11 | |
| SCHEMBL6459750 | 0.85 | P2RX7 (0.41) | P2RX7MEN1NR1I2KMT2AABCB11 | |
| SCHEMBL6459744 | 0.82 | MEN1 (0.39) | P2RX7MEN1NR1I2KMT2AABCB11 | |
| SCHEMBL6457871 | 0.81 | P2RX7 (0.35) | P2RX7MEN1NR1I2KMT2AABCB11 | |
| SCHEMBL6454146 | 0.81 | THRB (0.36) | P2RX7MEN1NR1I2KMT2AABCB11 | |
| SCHEMBL6461977 | 0.81 | THRB (0.36) | P2RX7MEN1NR1I2KMT2AABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1114046-B1 | INTERLEUKIN-5 INHIBITING 6-AZAURACIL DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2003-04-23 | — | — | EP | disclosed |