Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7142484 | 1.00 | RAB9A (0.36) | RAB9ANPC1PKMMEN1KMT2A | |
| SCHEMBL7140250 | 0.91 | RAB9A (0.39) | RAB9ANPC1PKMMEN1KMT2A | |
| SCHEMBL7140245 | 0.91 | RAB9A (0.39) | RAB9ANPC1PKMMEN1KMT2A | |
| SCHEMBL7137656 | 0.88 | SMN1; SMN2 (0.44) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL7137664 | 0.88 | SMN1; SMN2 (0.44) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL7164682 | 0.87 | AR (0.39) | ABCG2MAPTRELAMAOBPTPN5 | |
| SCHEMBL7164686 | 0.87 | AR (0.39) | ABCG2MAPTRELAMAOBPTPN5 | |
| SCHEMBL7133619 | 0.80 | PTPN5 (0.44) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL7133616 | 0.80 | PTPN5 (0.44) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL7139096 | 0.80 | MAOB (0.42) | MEN1KMT2AABCG2MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0996439-B1 | BETA-ALKOXYACRYLATES AGAINST MALARIA | HOFFMANN LA ROCHE (CH) | 2003-01-08 | — | — | EP | claimed |