Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7137664 | 1.00 | SMN1; SMN2 (0.44) | SMN1; SMN2MEN1KMT2AKDM4ELMNA | |
| SCHEMBL7140046 | 0.90 | MEN1 (0.44) | SMN1; SMN2MEN1KMT2AKDM4ELMNA | |
| SCHEMBL7140051 | 0.90 | MEN1 (0.44) | SMN1; SMN2MEN1KMT2AKDM4ELMNA | |
| SCHEMBL7142487 | 0.88 | RAB9A (0.36) | SMN1; SMN2MEN1KMT2AMAPTNPC1 | |
| SCHEMBL7142484 | 0.88 | RAB9A (0.36) | SMN1; SMN2MEN1KMT2AMAPTNPC1 | |
| SCHEMBL7139094 | 0.82 | MAOB (0.42) | MEN1KMT2ALMNATDP1NFE2L2 | |
| SCHEMBL7139096 | 0.82 | MAOB (0.42) | MEN1KMT2ALMNATDP1NFE2L2 | |
| SCHEMBL7140258 | 0.80 | LY96 (0.47) | MEN1KMT2AKDM4ELMNAHSP90AA1 | |
| SCHEMBL7140256 | 0.80 | LY96 (0.47) | MEN1KMT2AKDM4ELMNAHSP90AA1 | |
| SCHEMBL7135431 | 0.80 | NFE2L2 (0.44) | NFE2L2CYP1A1CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0996439-B1 | BETA-ALKOXYACRYLATES AGAINST MALARIA | HOFFMANN LA ROCHE (CH) | 2003-01-08 | — | — | EP | claimed |