Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 2/20 | 0.40 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7144266 | 0.81 | SMN1; SMN2 (0.41) | NQO2ALDH1A1KDM4EKMT2AHSD17B10 | |
| SCHEMBL4808825 | 0.81 | ALDH1A1 (0.47) | NQO2ALDH1A1KDM4EHSD17B10ALOX15 | |
| SCHEMBL3037889 | 0.80 | AKR1C3 (0.38) | ACACAKMT2AMEN1GAARAB9A | |
| SCHEMBL4809319 | 0.77 | ALDH1A1 (0.43) | NQO2ALDH1A1HSD17B10LMNAGAA | |
| SCHEMBL7149380 | 0.76 | BACE1 (0.41) | MAOAMAOBALDH1A1KDM4EKMT2A | |
| SCHEMBL3047058 | 0.73 | CYP3A4 (0.51) | NQO2ACACAALDH1A1KDM4EKMT2A | |
| SCHEMBL3052155 | 0.73 | ALDH1A1 (0.69) | NQO2ACACAALDH1A1KDM4EKMT2A | |
| SCHEMBL3047940 | 0.72 | GAA (0.45) | NQO2ALDH1A1KDM4EKMT2AHSD17B10 | |
| SCHEMBL3055530 | 0.71 | MAPT (0.56) | NQO2ACACAALDH1A1KDM4EKMT2A | |
| SCHEMBL20764930 | 0.70 | NQO2 (0.44) | NQO2ACACAALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1303272-A2 | BENZOTHIAZOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-04-23 | — | — | EP | disclosed |
| WO-2001097786-A2 | BENZOTHIAZOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2001-12-27 | — | — | WO | disclosed |