Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | COMT | P21964 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | FLT1 | P17948 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7142552 | 0.76 | NQO2 (0.40) | HPGDALDH1A1HSD17B10KDM4ERAB9A | |
| SCHEMBL3060568 | 0.70 | PDPK1 (0.47) | BACE1ALOX5HPGDALDH1A1BCL2L1 | |
| SCHEMBL3060565 | 0.66 | BCAT2 (0.39) | BACE1ALOX5ALDH1A1RETFLT1 | |
| SCHEMBL4337978 | 0.66 | LIMK1 (0.39) | BACE1HPGDALDH1A1BCL2L1HSD17B10 | |
| SCHEMBL124933 | 0.64 | PDPK1 (0.44) | HPGDALDH1A1HSD17B10COMTKDM4E | |
| SCHEMBL13210303 | 0.64 | BACE1 (0.59) | BACE1ALOX5HPGDALDH1A1BCL2L1 | |
| SCHEMBL12530867 | 0.63 | COMT (0.73) | ALDH1A1COMTHSP90AA1KDM4ERAB9A | |
| SCHEMBL21089511 | 0.62 | HPGD (0.48) | HPGDALDH1A1BCL2L1HSD17B10KDM4E | |
| SCHEMBL1889602 | 0.62 | IDO1 (0.65) | BACE1ALOX5HPGDALDH1A1BCL2L1 | |
| SCHEMBL30669867 | 0.62 | BACE1 (0.56) | BACE1ALOX5HPGDALDH1A1BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1303272-A2 | BENZOTHIAZOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-04-23 | — | — | EP | disclosed |
| WO-2001097786-A2 | BENZOTHIAZOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2001-12-27 | — | — | WO | disclosed |