Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 13/20 | 0.48 |
| ▸ | DRD5 | P21918 | 13/20 | 0.48 |
| ▸ | DRD2 | P14416 | 12/20 | 0.48 |
| ▸ | DRD3 | P35462 | 10/20 | 0.48 |
| ▸ | DRD4 | P21917 | 9/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12510367 | 0.82 | ALOX15 (0.41) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL7136783 | 0.81 | HPGD (0.58) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL7134438 | 0.78 | HPGD (0.46) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL13185710 | 0.74 | KMT2A (0.40) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL11712813 | 0.70 | DRD1 (0.50) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL7140651 | 0.69 | CES1 (0.47) | MAOAMAOBMEN1KMT2ATDP1 | |
| SCHEMBL13687357 | 0.69 | DPP8 (0.33) | POLBBRD4 | |
| SCHEMBL11707272 | 0.67 | DRD2 (0.42) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL7136766 | 0.67 | PDPK1 (0.47) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL11714310 | 0.66 | DRD2 (0.41) | DRD1DRD5DRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675887-B1 | ANTIALLERGIC TRIAZOLOBENZAZEPINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2003-04-02 | — | — | EP | disclosed |